Georg Thieme Verlag KG
Synthesis
,  volume 2008 ,  issue 15 ,  pages 2333-2336

A Facile and Improved Synthesis of 3-Fluorothiophene

MARTIN POMERANTZ 1
, 
Nashaat Turkman 2
1
 
Department of Chemistry & Biochemistry
2
 
Publication type: Journal Article
Publication date: 2008-07-08
Georg Thieme Verlag KG
scimago Q2
wos Q2
SJR: 0.559
CiteScore: 4.6
Impact factor: 2.3
ISSN: 00397881, 1437210X
Catalysis
Organic Chemistry
Abstract
A new efficient and convenient route to 3-fluorothiophene in four steps and 49% overall yield is reported. The fluorine atom was successfully introduced into the thiophene ring in 67% yield using the Schiemann reaction on 2-methoxycarbonylthiophene-3-diazonium tetrafluoroborate. The product, methyl 3-fluorothiophene-2-carboxylate was saponified and the 3-fluorothiophene-2-carboxylic acid was decarboxylated to afford 3-fluorothiophene in 93% yield.
Found 
Found 

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GOST |
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GOST Copy
POMERANTZ M., Turkman N. A Facile and Improved Synthesis of 3-Fluorothiophene // Synthesis. 2008. Vol. 2008. No. 15. pp. 2333-2336.
GOST all authors (up to 50) Copy
POMERANTZ M., Turkman N. A Facile and Improved Synthesis of 3-Fluorothiophene // Synthesis. 2008. Vol. 2008. No. 15. pp. 2333-2336.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1055/s-2008-1067170
UR - https://doi.org/10.1055/s-2008-1067170
TI - A Facile and Improved Synthesis of 3-Fluorothiophene
T2 - Synthesis
AU - POMERANTZ, MARTIN
AU - Turkman, Nashaat
PY - 2008
DA - 2008/07/08
PB - Georg Thieme Verlag KG
SP - 2333-2336
IS - 15
VL - 2008
SN - 0039-7881
SN - 1437-210X
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2008_POMERANTZ,
author = {MARTIN POMERANTZ and Nashaat Turkman},
title = {A Facile and Improved Synthesis of 3-Fluorothiophene},
journal = {Synthesis},
year = {2008},
volume = {2008},
publisher = {Georg Thieme Verlag KG},
month = {jul},
url = {https://doi.org/10.1055/s-2008-1067170},
number = {15},
pages = {2333--2336},
doi = {10.1055/s-2008-1067170}
}
MLA
Cite this
MLA Copy
POMERANTZ, MARTIN, and Nashaat Turkman. “A Facile and Improved Synthesis of 3-Fluorothiophene.” Synthesis, vol. 2008, no. 15, Jul. 2008, pp. 2333-2336. https://doi.org/10.1055/s-2008-1067170.