volume 53 issue 23 pages 4353-4374

Recent Advances in the Transition-Metal-Free Arylation of Hetero­arenes

Sefa Ucar
Arif Daştan
Publication typeJournal Article
Publication date2021-07-02
scimago Q2
wos Q2
SJR0.559
CiteScore4.6
Impact factor2.3
ISSN00397881, 1437210X
Catalysis
Organic Chemistry
Abstract

Transition-metal-free arylation reactions have attracted considerable attention for economic and environmental reasons over the past 40 years. In recent years, much effort has been made to develop efficient transition-metal-free approaches for the arylation of heteroarenes. Covering the literature from 2015 to early 2021, this review aims to provide a thorough overview of the synthetic and mechanistic aspects of these atom-economical and environmentally benign reactions.

1 Introduction

2 Arylation of Pre-functionalized Heteroarenes

2.1 Arylation of Heteroaryl Halides

2.2 Decarboxylative Arylation of Heteroarenes

3 Direct C–H Arylation of Heteroarenes

3.1 C(sp2)–H Arylation

3.2 C(sp3)–H Arylation

4 N-Arylation of Heteroarenes

5 Summary and Outlook

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American Chemical Society (ACS)
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Japan Academy
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Ucar S., Daştan A. Recent Advances in the Transition-Metal-Free Arylation of Hetero­arenes // Synthesis. 2021. Vol. 53. No. 23. pp. 4353-4374.
GOST all authors (up to 50) Copy
Ucar S., Daştan A. Recent Advances in the Transition-Metal-Free Arylation of Hetero­arenes // Synthesis. 2021. Vol. 53. No. 23. pp. 4353-4374.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1055/a-1543-3743
UR - https://doi.org/10.1055/a-1543-3743
TI - Recent Advances in the Transition-Metal-Free Arylation of Hetero­arenes
T2 - Synthesis
AU - Ucar, Sefa
AU - Daştan, Arif
PY - 2021
DA - 2021/07/02
PB - Georg Thieme Verlag KG
SP - 4353-4374
IS - 23
VL - 53
SN - 0039-7881
SN - 1437-210X
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2021_Ucar,
author = {Sefa Ucar and Arif Daştan},
title = {Recent Advances in the Transition-Metal-Free Arylation of Hetero­arenes},
journal = {Synthesis},
year = {2021},
volume = {53},
publisher = {Georg Thieme Verlag KG},
month = {jul},
url = {https://doi.org/10.1055/a-1543-3743},
number = {23},
pages = {4353--4374},
doi = {10.1055/a-1543-3743}
}
MLA
Cite this
MLA Copy
Ucar, Sefa, and Arif Daştan. “Recent Advances in the Transition-Metal-Free Arylation of Hetero­arenes.” Synthesis, vol. 53, no. 23, Jul. 2021, pp. 4353-4374. https://doi.org/10.1055/a-1543-3743.