Georg Thieme Verlag KG
Synthesis
,  том 54 ,  издание 14 ,  страницы 3249-3261

Design, Synthesis, and Screening of Pyridothieno[3,2-b]indole and Pyridothieno[3,2-c]cinnoline Derivatives as Potential Biologically Active Molecules

Тип публикации: Journal Article
Дата публикации: 2022-03-02
Georg Thieme Verlag KG
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SJR: 0.559
CiteScore: 4.6
Impact factor: 2.3
ISSN: 00397881, 1437210X
Catalysis
Organic Chemistry
Краткое описание

New pyridothieno[3,2-b]indole and pyridothieno[3,2-c]cinnoline derivatives are designed and prepared from the corresponding 3-amino-2-arylthieno[2,3-b]pyridines. By a molecular docking method novel potential inhibitors of DNA gyrase B are identified among the thieno[2,3-b]pyridine derivatives. In addition, some of the prepared pyridothienoindoles exhibit in vivo antidote activity against the herbicide 2,4-D.

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Stroganova T. A. et al. Design, Synthesis, and Screening of Pyridothieno[3,2-b]indole and Pyridothieno[3,2-c]cinnoline Derivatives as Potential Biologically Active Molecules // Synthesis. 2022. Vol. 54. No. 14. pp. 3249-3261.
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Stroganova T. A., Vasilin V. K., Kanishcheva E. A., Dmitrieva I. G., Taranenko V. V., Tumskiy R. S., Tumskaia A. V., Aksenov N. A., Krapivin G. D. Design, Synthesis, and Screening of Pyridothieno[3,2-b]indole and Pyridothieno[3,2-c]cinnoline Derivatives as Potential Biologically Active Molecules // Synthesis. 2022. Vol. 54. No. 14. pp. 3249-3261.
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TY - JOUR
DO - 10.1055/a-1785-7191
UR - https://doi.org/10.1055/a-1785-7191
TI - Design, Synthesis, and Screening of Pyridothieno[3,2-b]indole and Pyridothieno[3,2-c]cinnoline Derivatives as Potential Biologically Active Molecules
T2 - Synthesis
AU - Stroganova, Tatyana A
AU - Vasilin, Vladimir K
AU - Kanishcheva, Eugeniya A
AU - Dmitrieva, Irina G
AU - Taranenko, Viktor V
AU - Tumskiy, Roman S
AU - Tumskaia, Anastasiia V
AU - Aksenov, Nikolay A
AU - Krapivin, Gennady D
PY - 2022
DA - 2022/03/02
PB - Georg Thieme Verlag KG
SP - 3249-3261
IS - 14
VL - 54
SN - 0039-7881
SN - 1437-210X
ER -
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@article{2022_Stroganova,
author = {Tatyana A Stroganova and Vladimir K Vasilin and Eugeniya A Kanishcheva and Irina G Dmitrieva and Viktor V Taranenko and Roman S Tumskiy and Anastasiia V Tumskaia and Nikolay A Aksenov and Gennady D Krapivin},
title = {Design, Synthesis, and Screening of Pyridothieno[3,2-b]indole and Pyridothieno[3,2-c]cinnoline Derivatives as Potential Biologically Active Molecules},
journal = {Synthesis},
year = {2022},
volume = {54},
publisher = {Georg Thieme Verlag KG},
month = {mar},
url = {https://doi.org/10.1055/a-1785-7191},
number = {14},
pages = {3249--3261},
doi = {10.1055/a-1785-7191}
}
MLA
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Stroganova, Tatyana A., et al. “Design, Synthesis, and Screening of Pyridothieno[3,2-b]indole and Pyridothieno[3,2-c]cinnoline Derivatives as Potential Biologically Active Molecules.” Synthesis, vol. 54, no. 14, Mar. 2022, pp. 3249-3261. https://doi.org/10.1055/a-1785-7191.