Synthesis of isatins via oxone®/TBAI-mediated on-water oxidation of indoles

Publication type: Journal Article
Publication date: 2024-11-28
Georg Thieme Verlag KG
scimago Q2
wos Q2
SJR: 0.559
CiteScore: 4.6
Impact factor: 2.3
ISSN: 00397881, 1437210X
Abstract

Isatins and their derivatives are important scaffolds in a wide range of pharmaceuticals, bioactive compounds, and functional materials. Herein we describe a new strategy for the synthesis of isatins from indoles via Oxone®/TBAI-mediated oxidative dearomatization of indoles in water. The strategy works well with a variety of N-protected indoles and azaindoles.

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GOST Copy
Khajuria P. et al. Synthesis of isatins via oxone®/TBAI-mediated on-water oxidation of indoles // Synthesis. 2024.
GOST all authors (up to 50) Copy
Sawant S. D., Khajuria P., Bag D. Synthesis of isatins via oxone®/TBAI-mediated on-water oxidation of indoles // Synthesis. 2024.
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RIS Copy
TY - JOUR
DO - 10.1055/a-2492-3240
UR - http://www.thieme-connect.de/DOI/DOI?10.1055/a-2492-3240
TI - Synthesis of isatins via oxone®/TBAI-mediated on-water oxidation of indoles
T2 - Synthesis
AU - Sawant, Sanghapal D
AU - Khajuria, Pratiksha
AU - Bag, Debojyoti
PY - 2024
DA - 2024/11/28
PB - Georg Thieme Verlag KG
SN - 0039-7881
SN - 1437-210X
ER -
BibTex
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BibTex (up to 50 authors) Copy
@article{2024_Khajuria,
author = {Sanghapal D Sawant and Pratiksha Khajuria and Debojyoti Bag},
title = {Synthesis of isatins via oxone®/TBAI-mediated on-water oxidation of indoles},
journal = {Synthesis},
year = {2024},
publisher = {Georg Thieme Verlag KG},
month = {nov},
url = {http://www.thieme-connect.de/DOI/DOI?10.1055/a-2492-3240},
doi = {10.1055/a-2492-3240}
}