Synlett, volume 26, issue 12, pages 1687-1692
Sc(OTf)3-Catalyzed [3+3] Annulation of Cyclopropane 1,1-Diesters with β-(Indol-2-yl)-α,β-unsaturated Ketones: Synthesis of Polysubstituted Tetrahydrocarbazoles
Publication type: Journal Article
Publication date: 2015-05-04
Organic Chemistry
Abstract
A Sc(OTf)3-catalyzed cascade reaction consisting of a Friedel–Crafts alkylation followed by a Michael addition between cyclopropane 1,1-diesters and β-(indol-2-yl)-α,β-unsaturated ketones allows for the efficient synthesis of polysubstituted tetrahydrocarbazoles under very mild reaction conditions.
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Citations by publishers
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Chen W., Zhang H., Chen W. Sc(OTf)3-Catalyzed [3+3] Annulation of Cyclopropane 1,1-Diesters with β-(Indol-2-yl)-α,β-unsaturated Ketones: Synthesis of Polysubstituted Tetrahydrocarbazoles // Synlett. 2015. Vol. 26. No. 12. pp. 1687-1692.
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Chen W., Zhang H., Chen W. Sc(OTf)3-Catalyzed [3+3] Annulation of Cyclopropane 1,1-Diesters with β-(Indol-2-yl)-α,β-unsaturated Ketones: Synthesis of Polysubstituted Tetrahydrocarbazoles // Synlett. 2015. Vol. 26. No. 12. pp. 1687-1692.
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TY - JOUR
DO - 10.1055/s-0034-1380617
UR - https://doi.org/10.1055/s-0034-1380617
TI - Sc(OTf)3-Catalyzed [3+3] Annulation of Cyclopropane 1,1-Diesters with β-(Indol-2-yl)-α,β-unsaturated Ketones: Synthesis of Polysubstituted Tetrahydrocarbazoles
T2 - Synlett
AU - Chen, Wenhao
AU - Zhang, Huanhuan
AU - Chen, Wei
PY - 2015
DA - 2015/05/04 00:00:00
PB - Thieme
SP - 1687-1692
IS - 12
VL - 26
SN - 0936-5214
SN - 1437-2096
ER -
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@article{2015_Chen,
author = {Wenhao Chen and Huanhuan Zhang and Wei Chen},
title = {Sc(OTf)3-Catalyzed [3+3] Annulation of Cyclopropane 1,1-Diesters with β-(Indol-2-yl)-α,β-unsaturated Ketones: Synthesis of Polysubstituted Tetrahydrocarbazoles},
journal = {Synlett},
year = {2015},
volume = {26},
publisher = {Thieme},
month = {may},
url = {https://doi.org/10.1055/s-0034-1380617},
number = {12},
pages = {1687--1692},
doi = {10.1055/s-0034-1380617}
}
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Chen, Wenhao, et al. “Sc(OTf)3-Catalyzed [3+3] Annulation of Cyclopropane 1,1-Diesters with β-(Indol-2-yl)-α,β-unsaturated Ketones: Synthesis of Polysubstituted Tetrahydrocarbazoles.” Synlett, vol. 26, no. 12, May. 2015, pp. 1687-1692. https://doi.org/10.1055/s-0034-1380617.