volume 50 issue 18 pages 3738-3748

The Acid-Catalyzed 2-O-Alkylation of Substituted 2-Hydroxy-1,4-naphthoquinones by Alcohols: Versatile Preparative Synthesis of Spinochrome D and Its 6-Alkoxy Derivatives

Sergey Polonik
Yuri Sabutskii
Vladimir Denisenko
Publication typeJournal Article
Publication date2018-07-12
scimago Q2
wos Q2
SJR0.559
CiteScore4.6
Impact factor2.3
ISSN00397881, 1437210X
Catalysis
Organic Chemistry
Abstract

A series of substituted 2-alkoxy-1,4-naphthoquinone derivatives were obtained by acid-catalyzed condensation of substituted 2-hydroxy-1,4-naphthoquinones with propan-1-ol, butan-1-ol, or pentan-1-ol in good yields. Based on this reaction a versatile preparative synthesis of spinochrome D was developed.

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Polonik S., Sabutskii Y., Denisenko V. The Acid-Catalyzed 2-O-Alkylation of Substituted 2-Hydroxy-1,4-naphthoquinones by Alcohols: Versatile Preparative Synthesis of Spinochrome D and Its 6-Alkoxy Derivatives // Synthesis. 2018. Vol. 50. No. 18. pp. 3738-3748.
GOST all authors (up to 50) Copy
Polonik S., Sabutskii Y., Denisenko V. The Acid-Catalyzed 2-O-Alkylation of Substituted 2-Hydroxy-1,4-naphthoquinones by Alcohols: Versatile Preparative Synthesis of Spinochrome D and Its 6-Alkoxy Derivatives // Synthesis. 2018. Vol. 50. No. 18. pp. 3738-3748.
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TY - JOUR
DO - 10.1055/s-0037-1610415
UR - https://doi.org/10.1055/s-0037-1610415
TI - The Acid-Catalyzed 2-O-Alkylation of Substituted 2-Hydroxy-1,4-naphthoquinones by Alcohols: Versatile Preparative Synthesis of Spinochrome D and Its 6-Alkoxy Derivatives
T2 - Synthesis
AU - Polonik, Sergey
AU - Sabutskii, Yuri
AU - Denisenko, Vladimir
PY - 2018
DA - 2018/07/12
PB - Georg Thieme Verlag KG
SP - 3738-3748
IS - 18
VL - 50
SN - 0039-7881
SN - 1437-210X
ER -
BibTex |
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BibTex (up to 50 authors) Copy
@article{2018_Polonik,
author = {Sergey Polonik and Yuri Sabutskii and Vladimir Denisenko},
title = {The Acid-Catalyzed 2-O-Alkylation of Substituted 2-Hydroxy-1,4-naphthoquinones by Alcohols: Versatile Preparative Synthesis of Spinochrome D and Its 6-Alkoxy Derivatives},
journal = {Synthesis},
year = {2018},
volume = {50},
publisher = {Georg Thieme Verlag KG},
month = {jul},
url = {https://doi.org/10.1055/s-0037-1610415},
number = {18},
pages = {3738--3748},
doi = {10.1055/s-0037-1610415}
}
MLA
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Polonik, Sergey, et al. “The Acid-Catalyzed 2-O-Alkylation of Substituted 2-Hydroxy-1,4-naphthoquinones by Alcohols: Versatile Preparative Synthesis of Spinochrome D and Its 6-Alkoxy Derivatives.” Synthesis, vol. 50, no. 18, Jul. 2018, pp. 3738-3748. https://doi.org/10.1055/s-0037-1610415.