Metal-Free Hydroamination of Alkynes: A Mild and Concise Synthesis of Thiazolo[3,2-a]indoles and their Cytotoxic Activity
2
School of Pharmacy, Philadelphia College of Osteopathic Medicine
|
Publication type: Journal Article
Publication date: 2019-09-24
scimago Q2
wos Q2
SJR: 0.559
CiteScore: 4.6
Impact factor: 2.3
ISSN: 00397881, 1437210X
Catalysis
Organic Chemistry
Abstract
A metal-free, mild and efficient method for the synthesis of thiazolo[3,2-a]indoles has been developed starting from indoline-2-thiones. The reaction methodology involves first the formation of thermally labile 2-(prop-2-ynylthio)-1H-indole intermediates, which undergo base-mediated intramolecular hydroamination to produce the title compounds in excellent yields.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
|
|
|
Journal of Organic Chemistry
4 publications, 25%
|
|
|
Organic Letters
2 publications, 12.5%
|
|
|
Asian Journal of Organic Chemistry
2 publications, 12.5%
|
|
|
Tetrahedron Letters
1 publication, 6.25%
|
|
|
Chemistry - A European Journal
1 publication, 6.25%
|
|
|
Advanced Synthesis and Catalysis
1 publication, 6.25%
|
|
|
Organic Chemistry Frontiers
1 publication, 6.25%
|
|
|
European Journal of Organic Chemistry
1 publication, 6.25%
|
|
|
Mendeleev Communications
1 publication, 6.25%
|
|
|
Tetrahedron
1 publication, 6.25%
|
|
|
1
2
3
4
|
Publishers
|
1
2
3
4
5
6
|
|
|
Wiley
6 publications, 37.5%
|
|
|
American Chemical Society (ACS)
6 publications, 37.5%
|
|
|
Elsevier
2 publications, 12.5%
|
|
|
Royal Society of Chemistry (RSC)
1 publication, 6.25%
|
|
|
OOO Zhurnal "Mendeleevskie Soobshcheniya"
1 publication, 6.25%
|
|
|
1
2
3
4
5
6
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
16
Total citations:
16
Citations from 2025:
4
(25%)
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Short S. et al. Metal-Free Hydroamination of Alkynes: A Mild and Concise Synthesis of Thiazolo[3,2-a]indoles and their Cytotoxic Activity // Synthesis. 2019. Vol. 51. No. 22. pp. 4263-4270.
GOST all authors (up to 50)
Copy
Short S., Rhodes S., Bhave V. S., Hojo R., Jha M. Metal-Free Hydroamination of Alkynes: A Mild and Concise Synthesis of Thiazolo[3,2-a]indoles and their Cytotoxic Activity // Synthesis. 2019. Vol. 51. No. 22. pp. 4263-4270.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1055/s-0039-1690680
UR - https://doi.org/10.1055/s-0039-1690680
TI - Metal-Free Hydroamination of Alkynes: A Mild and Concise Synthesis of Thiazolo[3,2-a]indoles and their Cytotoxic Activity
T2 - Synthesis
AU - Short, Spencer
AU - Rhodes, Steven
AU - Bhave, Vishakha S.
AU - Hojo, Ryoga
AU - Jha, M.
PY - 2019
DA - 2019/09/24
PB - Georg Thieme Verlag KG
SP - 4263-4270
IS - 22
VL - 51
SN - 0039-7881
SN - 1437-210X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2019_Short,
author = {Spencer Short and Steven Rhodes and Vishakha S. Bhave and Ryoga Hojo and M. Jha},
title = {Metal-Free Hydroamination of Alkynes: A Mild and Concise Synthesis of Thiazolo[3,2-a]indoles and their Cytotoxic Activity},
journal = {Synthesis},
year = {2019},
volume = {51},
publisher = {Georg Thieme Verlag KG},
month = {sep},
url = {https://doi.org/10.1055/s-0039-1690680},
number = {22},
pages = {4263--4270},
doi = {10.1055/s-0039-1690680}
}
Cite this
MLA
Copy
Short, Spencer, et al. “Metal-Free Hydroamination of Alkynes: A Mild and Concise Synthesis of Thiazolo[3,2-a]indoles and their Cytotoxic Activity.” Synthesis, vol. 51, no. 22, Sep. 2019, pp. 4263-4270. https://doi.org/10.1055/s-0039-1690680.