N-Substituted Ureas and Thioureas in Biginelli Reaction Promoted by Chlorotrimethylsilane: Convenient Synthesis of N1-Alkyl-, N1-Aryl-, and N1,N3-Dialkyl-3,4-Dihydropyrimidin-2(1H)-(thi)ones
Publication type: Journal Article
Publication date: 2007-02-01
scimago Q2
wos Q2
SJR: 0.559
CiteScore: 4.6
Impact factor: 2.3
ISSN: 00397881, 1437210X
Catalysis
Organic Chemistry
Abstract
The classical Biginelli reaction has been extended by the use of N-substituted ureas and thioureas. A set of N1 -alkyl-, N1-aryl-, and N1,N3 -dialkyl-3,4-dihydropyrimidin -2(1H) -(thi )ones was readily prepared in excellent yield when chlorotrimethylsilane in N,N-dimethylformamide was used as promoter and water scavenger.
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Total citations:
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GOST
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Ryabukhin S. V. et al. N-Substituted Ureas and Thioureas in Biginelli Reaction Promoted by Chlorotrimethylsilane: Convenient Synthesis of N1-Alkyl-, N1-Aryl-, and N1,N3-Dialkyl-3,4-Dihydropyrimidin-2(1H)-(thi)ones // Synthesis. 2007. Vol. 2007. No. 3. pp. 417-427.
GOST all authors (up to 50)
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Ryabukhin S. V., Ryabukhin S., Plaskon A., Volochnyuk D. M., Tolmachev A. N-Substituted Ureas and Thioureas in Biginelli Reaction Promoted by Chlorotrimethylsilane: Convenient Synthesis of N1-Alkyl-, N1-Aryl-, and N1,N3-Dialkyl-3,4-Dihydropyrimidin-2(1H)-(thi)ones // Synthesis. 2007. Vol. 2007. No. 3. pp. 417-427.
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RIS
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TY - JOUR
DO - 10.1055/s-2007-965881
UR - https://doi.org/10.1055/s-2007-965881
TI - N-Substituted Ureas and Thioureas in Biginelli Reaction Promoted by Chlorotrimethylsilane: Convenient Synthesis of N1-Alkyl-, N1-Aryl-, and N1,N3-Dialkyl-3,4-Dihydropyrimidin-2(1H)-(thi)ones
T2 - Synthesis
AU - Ryabukhin, Sergey V.
AU - Ryabukhin, Sergey
AU - Plaskon, Andrey
AU - Volochnyuk, Dmitriy M.
AU - Tolmachev, Andrey
PY - 2007
DA - 2007/02/01
PB - Georg Thieme Verlag KG
SP - 417-427
IS - 3
VL - 2007
SN - 0039-7881
SN - 1437-210X
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2007_Ryabukhin,
author = {Sergey V. Ryabukhin and Sergey Ryabukhin and Andrey Plaskon and Dmitriy M. Volochnyuk and Andrey Tolmachev},
title = {N-Substituted Ureas and Thioureas in Biginelli Reaction Promoted by Chlorotrimethylsilane: Convenient Synthesis of N1-Alkyl-, N1-Aryl-, and N1,N3-Dialkyl-3,4-Dihydropyrimidin-2(1H)-(thi)ones},
journal = {Synthesis},
year = {2007},
volume = {2007},
publisher = {Georg Thieme Verlag KG},
month = {feb},
url = {https://doi.org/10.1055/s-2007-965881},
number = {3},
pages = {417--427},
doi = {10.1055/s-2007-965881}
}
Cite this
MLA
Copy
Ryabukhin, Sergey V., et al. “N-Substituted Ureas and Thioureas in Biginelli Reaction Promoted by Chlorotrimethylsilane: Convenient Synthesis of N1-Alkyl-, N1-Aryl-, and N1,N3-Dialkyl-3,4-Dihydropyrimidin-2(1H)-(thi)ones.” Synthesis, vol. 2007, no. 3, Feb. 2007, pp. 417-427. https://doi.org/10.1055/s-2007-965881.
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