,
volume 2064
Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis
Publication type: Proceedings Article
Publication date: 2019-01-16
SJR: 0.153
CiteScore: 0.5
Impact factor: —
ISSN: 0094243X, 15517616
Abstract
A modification method of the target for Matrix Assisted Laser Desorption/Ionization (MALDI) analysis by metal-affinity sorbents was proposed. Monolayers of metal stearates obtained in the geometry of the drop perform as such sorbents. The formation of monolayers was proved by optical microscopy and the Laser Desorption/Ionization (LDI) method. The surface of the substrate after modification studied using scanning electron microscopy. Metal-affinity extraction of human serum albumin adducts with soman was carried out at the modified target surface. MALDI mass spectrometric analysis demonstrated that signals corresponding to adducts are present in mass spectra.A modification method of the target for Matrix Assisted Laser Desorption/Ionization (MALDI) analysis by metal-affinity sorbents was proposed. Monolayers of metal stearates obtained in the geometry of the drop perform as such sorbents. The formation of monolayers was proved by optical microscopy and the Laser Desorption/Ionization (LDI) method. The surface of the substrate after modification studied using scanning electron microscopy. Metal-affinity extraction of human serum albumin adducts with soman was carried out at the modified target surface. MALDI mass spectrometric analysis demonstrated that signals corresponding to adducts are present in mass spectra.
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Silyavka E. S. et al. Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis // AIP Conference Proceedings. 2019. Vol. 2064.
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Silyavka E. S., Selyutin A. A., Sukhodolov N. G., V.V. S., Oleneva P. A., Mitrofanov A., Keltsieva O. A., Dubakova P. S., Babakov V. N., Alexandrova M. L., Krasnov N. V., Podolskaya E. P. Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis // AIP Conference Proceedings. 2019. Vol. 2064.
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TY - CPAPER
DO - 10.1063/1.5087677
UR - https://doi.org/10.1063/1.5087677
TI - Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis
T2 - AIP Conference Proceedings
AU - Silyavka, E S
AU - Selyutin, A A
AU - Sukhodolov, N G
AU - V.V., Shilovskikh
AU - Oleneva, P A
AU - Mitrofanov, A.A.
AU - Keltsieva, O A
AU - Dubakova, P S
AU - Babakov, V. N.
AU - Alexandrova, M L
AU - Krasnov, N V
AU - Podolskaya, E P
PY - 2019
DA - 2019/01/16
PB - AIP Publishing
VL - 2064
SN - 0094-243X
SN - 1551-7616
ER -
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@inproceedings{2019_Silyavka,
author = {E S Silyavka and A A Selyutin and N G Sukhodolov and Shilovskikh V.V. and P A Oleneva and A.A. Mitrofanov and O A Keltsieva and P S Dubakova and V. N. Babakov and M L Alexandrova and N V Krasnov and E P Podolskaya},
title = {Collapsed monomolecular thin films as surface nanomodification techniques for bioorganic MALDI analysis},
year = {2019},
volume = {2064},
month = {jan},
publisher = {AIP Publishing}
}