Open Access
Open access
Russian Chemical Reviews, volume 88, issue 6, pages 644-676

Tetrazoles for biomedicine

Elena A. Popova
, 
Rostislav E. Trifonov
, 
Vladimir A Ostrovskii
Publication type: Journal Article
Publication date: 2019-06-01
scimago Q1
SJR: 0.890
CiteScore: 13.0
Impact factor: 7
ISSN: 0036021X, 14684837
General Chemistry
Abstract

The tetrazole ring is an important pharmacophore. It is a structural component in many drugs, drug candidates (or lead compounds) and various biochemical reagents. This review summarizes data on the use of tetrazoles in biomedicine published in the last 10 – 15 years and also views on the nature of their biological effects. The prospects for the development of new biologically active substances containing a tetrazolyl pharmacophore are analyzed.

The bibliography includes 263 references.

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