Open Access
Open access
Journal of Biological Chemistry, volume 284, issue 34, pages 22507-22511

Glycine N-Methyltransferase and Regulation of S-Adenosylmethionine Levels

Luka Zigmund 1
Mudd S. Harvey 2
Wagner Conrad 1
1
 
From the ‡Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee 37232
2
 
the §Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, Maryland 20892
Publication typeJournal Article
Publication date2009-08-01
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor4.8
ISSN00219258, 1083351X
Biochemistry
Molecular Biology
Cell Biology
Abstract
Methylation is a major biological process. It has been shown to be important in formation of compounds such as phosphatidylcholine, creatine, and many others and also participates in epigenetic effects through methylation of histones and DNA. The donor of methyl groups for almost all cellular methylation reactions is S-adenosylmethionine. It seems that the level of S-adenosylmethionine must be regulated in response to developmental stages and metabolic changes, and the enzyme glycine N-methyltransferase has been shown to play a major role in such regulation in mammals. This minireview will focus on the latest discoveries in the elucidation of the mechanism of that regulation.

Citations by journals

1
2
3
4
5
Scientific Reports
Scientific Reports, 5, 3.31%
Scientific Reports
5 publications, 3.31%
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 4, 2.65%
International Journal of Molecular Sciences
4 publications, 2.65%
Journal of Nutrition
Journal of Nutrition, 4, 2.65%
Journal of Nutrition
4 publications, 2.65%
Aging Cell
Aging Cell, 4, 2.65%
Aging Cell
4 publications, 2.65%
Nutrients
Nutrients, 3, 1.99%
Nutrients
3 publications, 1.99%
Amino Acids
Amino Acids, 3, 1.99%
Amino Acids
3 publications, 1.99%
Hepatology
Hepatology, 2, 1.32%
Hepatology
2 publications, 1.32%
Biomolecules
Biomolecules, 2, 1.32%
Biomolecules
2 publications, 1.32%
Metabolites
Metabolites, 2, 1.32%
Metabolites
2 publications, 1.32%
Molecular Genetics and Metabolism
Molecular Genetics and Metabolism, 2, 1.32%
Molecular Genetics and Metabolism
2 publications, 1.32%
iScience
iScience, 2, 1.32%
iScience
2 publications, 1.32%
PLoS ONE
PLoS ONE, 2, 1.32%
PLoS ONE
2 publications, 1.32%
Biochimica et Biophysica Acta - Proteins and Proteomics
Biochimica et Biophysica Acta - Proteins and Proteomics, 2, 1.32%
Biochimica et Biophysica Acta - Proteins and Proteomics
2 publications, 1.32%
Cell Reports
Cell Reports, 2, 1.32%
Cell Reports
2 publications, 1.32%
Biomedical Chromatography
Biomedical Chromatography, 2, 1.32%
Biomedical Chromatography
2 publications, 1.32%
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2, 1.32%
Proceedings of the National Academy of Sciences of the United States of America
2 publications, 1.32%
Annual Review of Nutrition
Annual Review of Nutrition, 2, 1.32%
Annual Review of Nutrition
2 publications, 1.32%
Biomolecular NMR Assignments
Biomolecular NMR Assignments, 1, 0.66%
Biomolecular NMR Assignments
1 publication, 0.66%
Wellcome Open Research
Wellcome Open Research, 1, 0.66%
Wellcome Open Research
1 publication, 0.66%
Oncotarget
Oncotarget, 1, 0.66%
Oncotarget
1 publication, 0.66%
Antioxidants and Redox Signaling
Antioxidants and Redox Signaling, 1, 0.66%
Antioxidants and Redox Signaling
1 publication, 0.66%
PeerJ
PeerJ, 1, 0.66%
PeerJ
1 publication, 0.66%
Biochemical Journal
Biochemical Journal, 1, 0.66%
Biochemical Journal
1 publication, 0.66%
European Journal of Gastroenterology and Hepatology
European Journal of Gastroenterology and Hepatology, 1, 0.66%
European Journal of Gastroenterology and Hepatology
1 publication, 0.66%
Exercise and Sport Sciences Reviews
Exercise and Sport Sciences Reviews, 1, 0.66%
Exercise and Sport Sciences Reviews
1 publication, 0.66%
Journal of Urology
Journal of Urology, 1, 0.66%
Journal of Urology
1 publication, 0.66%
World Journal of Biological Chemistry
World Journal of Biological Chemistry, 1, 0.66%
World Journal of Biological Chemistry
1 publication, 0.66%
Animals
Animals, 1, 0.66%
Animals
1 publication, 0.66%
Microorganisms
Microorganisms, 1, 0.66%
Microorganisms
1 publication, 0.66%
1
2
3
4
5

Citations by publishers

5
10
15
20
25
30
35
Elsevier
Elsevier, 32, 21.19%
Elsevier
32 publications, 21.19%
Springer Nature
Springer Nature, 23, 15.23%
Springer Nature
23 publications, 15.23%
Wiley
Wiley, 16, 10.6%
Wiley
16 publications, 10.6%
Multidisciplinary Digital Publishing Institute (MDPI)
Multidisciplinary Digital Publishing Institute (MDPI), 15, 9.93%
Multidisciplinary Digital Publishing Institute (MDPI)
15 publications, 9.93%
Taylor & Francis
Taylor & Francis, 5, 3.31%
Taylor & Francis
5 publications, 3.31%
American Society for Nutrition
American Society for Nutrition, 5, 3.31%
American Society for Nutrition
5 publications, 3.31%
American Chemical Society (ACS)
American Chemical Society (ACS), 5, 3.31%
American Chemical Society (ACS)
5 publications, 3.31%
Public Library of Science (PLoS)
Public Library of Science (PLoS), 3, 1.99%
Public Library of Science (PLoS)
3 publications, 1.99%
Annual Reviews
Annual Reviews, 3, 1.99%
Annual Reviews
3 publications, 1.99%
Wolters Kluwer Health
Wolters Kluwer Health, 2, 1.32%
Wolters Kluwer Health
2 publications, 1.32%
Frontiers Media S.A.
Frontiers Media S.A., 2, 1.32%
Frontiers Media S.A.
2 publications, 1.32%
American Association for the Advancement of Science (AAAS)
American Association for the Advancement of Science (AAAS), 2, 1.32%
American Association for the Advancement of Science (AAAS)
2 publications, 1.32%
Proceedings of the National Academy of Sciences (PNAS)
Proceedings of the National Academy of Sciences (PNAS), 2, 1.32%
Proceedings of the National Academy of Sciences (PNAS)
2 publications, 1.32%
Impact Journals
Impact Journals, 1, 0.66%
Impact Journals
1 publication, 0.66%
Mary Ann Liebert
Mary Ann Liebert, 1, 0.66%
Mary Ann Liebert
1 publication, 0.66%
PeerJ
PeerJ, 1, 0.66%
PeerJ
1 publication, 0.66%
Portland Press
Portland Press, 1, 0.66%
Portland Press
1 publication, 0.66%
Baishideng Publishing Group
Baishideng Publishing Group, 1, 0.66%
Baishideng Publishing Group
1 publication, 0.66%
Feinstein Institute for Medical Research, 1, 0.66%
Feinstein Institute for Medical Research
1 publication, 0.66%
American Society for Biochemistry and Molecular Biology
American Society for Biochemistry and Molecular Biology, 1, 0.66%
American Society for Biochemistry and Molecular Biology
1 publication, 0.66%
KeAi Communications Co.
KeAi Communications Co., 1, 0.66%
KeAi Communications Co.
1 publication, 0.66%
Environmental Health Perspectives
Environmental Health Perspectives, 1, 0.66%
Environmental Health Perspectives
1 publication, 0.66%
Royal Society of Chemistry (RSC)
Royal Society of Chemistry (RSC), 1, 0.66%
Royal Society of Chemistry (RSC)
1 publication, 0.66%
Food Safety Commission, Cabinet Office", 1, 0.66%
Food Safety Commission, Cabinet Office"
1 publication, 0.66%
, 1, 0.66%
1 publication, 0.66%
Optical Society of America
Optical Society of America, 1, 0.66%
Optical Society of America
1 publication, 0.66%
SAGE
SAGE, 1, 0.66%
SAGE
1 publication, 0.66%
Oxford University Press
Oxford University Press, 1, 0.66%
Oxford University Press
1 publication, 0.66%
American Association for Clinical Chemistry
American Association for Clinical Chemistry, 1, 0.66%
American Association for Clinical Chemistry
1 publication, 0.66%
5
10
15
20
25
30
35
  • We do not take into account publications that without a DOI.
  • Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
  • Statistics recalculated weekly.
Metrics
Share
Cite this
GOST |
Cite this
GOST Copy
Luka Z., Mudd S. H., Wagner C. Glycine N-Methyltransferase and Regulation of S-Adenosylmethionine Levels // Journal of Biological Chemistry. 2009. Vol. 284. No. 34. pp. 22507-22511.
GOST all authors (up to 50) Copy
Luka Z., Mudd S. H., Wagner C. Glycine N-Methyltransferase and Regulation of S-Adenosylmethionine Levels // Journal of Biological Chemistry. 2009. Vol. 284. No. 34. pp. 22507-22511.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1074/jbc.R109.019273
UR - https://doi.org/10.1074%2Fjbc.R109.019273
TI - Glycine N-Methyltransferase and Regulation of S-Adenosylmethionine Levels
T2 - Journal of Biological Chemistry
AU - Luka, Zigmund
AU - Mudd, S. Harvey
AU - Wagner, Conrad
PY - 2009
DA - 2009/08/01 00:00:00
PB - American Society for Biochemistry and Molecular Biology
SP - 22507-22511
IS - 34
VL - 284
PMID - 19483083
SN - 0021-9258
SN - 1083-351X
ER -
BibTex |
Cite this
BibTex Copy
@article{2009_Luka,
author = {Zigmund Luka and S. Harvey Mudd and Conrad Wagner},
title = {Glycine N-Methyltransferase and Regulation of S-Adenosylmethionine Levels},
journal = {Journal of Biological Chemistry},
year = {2009},
volume = {284},
publisher = {American Society for Biochemistry and Molecular Biology},
month = {aug},
url = {https://doi.org/10.1074%2Fjbc.R109.019273},
number = {34},
pages = {22507--22511},
doi = {10.1074/jbc.R109.019273}
}
MLA
Cite this
MLA Copy
Luka, Zigmund, et al. “Glycine N-Methyltransferase and Regulation of S-Adenosylmethionine Levels.” Journal of Biological Chemistry, vol. 284, no. 34, Aug. 2009, pp. 22507-22511. https://doi.org/10.1074%2Fjbc.R109.019273.
Found error?