Convenient and Efficient Synthesis of Some Novel Fused Thieno Pyrimidines Using Gewald's Reaction
Ramakrishna Nirogi
1
,
Rama Sastri Kambhampati
1
,
Prabhakar Kothmirkar
1
,
Sobhanadri Arepalli
1
,
Narasimha Reddy G Pamuleti
1
,
Anil K Shinde
1
,
P. K. Dubey
2
1
Discovery Research, Medicinal Chemistry, Suven Life Sciences Ltd. , Hyderabad , Andhra Pradesh , India
|
Publication type: Journal Article
Publication date: 2011-10-01
scimago Q3
wos Q3
SJR: 0.322
CiteScore: 4.3
Impact factor: 1.8
ISSN: 00397911, 15322432
Organic Chemistry
Abstract
Several functionalized thienopyrimidines were synthesized by a facile synthetic method, which includes Gewald's reaction, and were characterized by spectral and analytical data. These functionalized thienopyrimidines were converted to various new chemical entities of biological importance, such as 2-piperazinymethyl thienopyrimidines (6, 8), 4-dimethylaminoethoxy thienopyrimidines (11), and 3-dimethylaminoethyl thienopyrimidines (12). All the compounds thus synthesized were screened for their invitro biological activities. Some of the compounds displayed promising serotonin 5-HT6 receptor antagonist activities.
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Total citations:
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Citations from 2024:
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GOST
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Nirogi R. et al. Convenient and Efficient Synthesis of Some Novel Fused Thieno Pyrimidines Using Gewald's Reaction // Synthetic Communications. 2011. Vol. 41. No. 19. pp. 2835-2851.
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Nirogi R., Kambhampati R. S., Kothmirkar P., Arepalli S., Pamuleti N. R. G., Shinde A. K., Dubey P. K. Convenient and Efficient Synthesis of Some Novel Fused Thieno Pyrimidines Using Gewald's Reaction // Synthetic Communications. 2011. Vol. 41. No. 19. pp. 2835-2851.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1080/00397911.2010.515357
UR - https://doi.org/10.1080/00397911.2010.515357
TI - Convenient and Efficient Synthesis of Some Novel Fused Thieno Pyrimidines Using Gewald's Reaction
T2 - Synthetic Communications
AU - Nirogi, Ramakrishna
AU - Kambhampati, Rama Sastri
AU - Kothmirkar, Prabhakar
AU - Arepalli, Sobhanadri
AU - Pamuleti, Narasimha Reddy G
AU - Shinde, Anil K
AU - Dubey, P. K.
PY - 2011
DA - 2011/10/01
PB - Taylor & Francis
SP - 2835-2851
IS - 19
VL - 41
SN - 0039-7911
SN - 1532-2432
ER -
Cite this
BibTex (up to 50 authors)
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@article{2011_Nirogi,
author = {Ramakrishna Nirogi and Rama Sastri Kambhampati and Prabhakar Kothmirkar and Sobhanadri Arepalli and Narasimha Reddy G Pamuleti and Anil K Shinde and P. K. Dubey},
title = {Convenient and Efficient Synthesis of Some Novel Fused Thieno Pyrimidines Using Gewald's Reaction},
journal = {Synthetic Communications},
year = {2011},
volume = {41},
publisher = {Taylor & Francis},
month = {oct},
url = {https://doi.org/10.1080/00397911.2010.515357},
number = {19},
pages = {2835--2851},
doi = {10.1080/00397911.2010.515357}
}
Cite this
MLA
Copy
Nirogi, Ramakrishna, et al. “Convenient and Efficient Synthesis of Some Novel Fused Thieno Pyrimidines Using Gewald's Reaction.” Synthetic Communications, vol. 41, no. 19, Oct. 2011, pp. 2835-2851. https://doi.org/10.1080/00397911.2010.515357.