Synthetic Communications, volume 28, issue 23, pages 4393-4400

A Facile Route to 9-Phosphorylated Neuraminic Acid Derivatives

Marcos Carolirezende ¹

Silvia Sepúlvedaboza ²

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Facultad de Química y Biologia , Universidad de Santiago de Chile , Av. B.O'Higgins, Santiago, 3363, Chile |

Facultad de Ciencias Médicas , Universidad de Santiago de Chile , Av. B.O'Higgins, Santiago, 3363, Chile |

Publication type: Journal Article

Publication date: 1998-12-01

Taylor & Francis

Journal: Synthetic Communications

scimago Q3

SJR: 0.323

CiteScore: 4.4

Impact factor: 1.8

ISSN: 00397911, 15322432

DOI: 10.1080/00397919808004474

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Organic Chemistry

Abstract

The phosphitylation of 2-α-O-Benzyl-N-acetylneuraminic acid (2) and of the methyl 2-α-O-methyl-N-acetylneuraminate (3) with 2-chloro-4H-1,2,3-benzodioxaphosphorin-4-one (4) is described. The reaction affords a ready access to 9-phosphorylated derivatives of N-acetylneuraminic acid (1).

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Publisher

Taylor & Francis

Journal

Synthetic Communications

scimago Q3

SJR

0.323

CiteScore

4.4

Impact factor

1.8

ISSN

00397911 (Print)

15322432 (Electronic)