Preparation of Imino and Amino N-15 Enriched 2-Aminopurine Deoxynucleoside
Publication type: Journal Article
Publication date: 1989-01-01
Biochemistry
Genetics
Abstract
Abstract We report the synthesis of N-15 enriched 2-aminopurine-2′-deoxynucleoside (APdR). Both ring and 2-amino nitrogens were labelled via a Dimroth rearrangement of the free base. The corresponding deoxynucleoside was prepared enzymatically. Results of both proton and N-15 NMR studies show that the predominant tautomeric form of APdR is amino and the N1 position is shown to be the site of protonation.
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11
Total citations:
11
Citations from 2024:
2
(18%)
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GOST
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Sowers L. C. et al. Preparation of Imino and Amino N-15 Enriched 2-Aminopurine Deoxynucleoside // Nucleosides and Nucleotides. 1989. Vol. 8. No. 1. pp. 23-34.
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Sowers L. C., Mhaskar D. N., Khwaja T. A., Goodman M. F. Preparation of Imino and Amino N-15 Enriched 2-Aminopurine Deoxynucleoside // Nucleosides and Nucleotides. 1989. Vol. 8. No. 1. pp. 23-34.
Cite this
RIS
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TY - JOUR
DO - 10.1080/07328318908054155
UR - https://doi.org/10.1080/07328318908054155
TI - Preparation of Imino and Amino N-15 Enriched 2-Aminopurine Deoxynucleoside
T2 - Nucleosides and Nucleotides
AU - Sowers, Lawrence C.
AU - Mhaskar, Dhananjaya N
AU - Khwaja, Tasneem A.
AU - Goodman, Myron F.
PY - 1989
DA - 1989/01/01
PB - Taylor & Francis
SP - 23-34
IS - 1
VL - 8
SN - 0732-8311
ER -
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BibTex (up to 50 authors)
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@article{1989_Sowers,
author = {Lawrence C. Sowers and Dhananjaya N Mhaskar and Tasneem A. Khwaja and Myron F. Goodman},
title = {Preparation of Imino and Amino N-15 Enriched 2-Aminopurine Deoxynucleoside},
journal = {Nucleosides and Nucleotides},
year = {1989},
volume = {8},
publisher = {Taylor & Francis},
month = {jan},
url = {https://doi.org/10.1080/07328318908054155},
number = {1},
pages = {23--34},
doi = {10.1080/07328318908054155}
}
Cite this
MLA
Copy
Sowers, Lawrence C., et al. “Preparation of Imino and Amino N-15 Enriched 2-Aminopurine Deoxynucleoside.” Nucleosides and Nucleotides, vol. 8, no. 1, Jan. 1989, pp. 23-34. https://doi.org/10.1080/07328318908054155.