Microbial metabolism. Part 10: Metabolites of 7,8-dimethoxyflavone and 5-methoxyflavone
Publication type: Journal Article
Publication date: 2009-09-10
scimago Q2
wos Q3
SJR: 0.398
CiteScore: 5.2
Impact factor: 1.6
ISSN: 14786419, 14786427
PubMed ID:
19731142
Organic Chemistry
Biochemistry
Plant Science
Analytical Chemistry
Abstract
Microbial transformation of 7,8-dimethoxyflavone (1) by Mucor ramannianus produced five metabolites: 7,8-dimethoxy-4'-hydroxyflavone (2), 3',4'-dihydroxy-7,8-dimethoxyflavone (3), 7,3'-dihydroxy-8-methoxyflavone (4), 7,4'-dihydroxy-8-methoxyflavone (5) and 8-methoxy-7,3',4'-trihydroxyflavone (6). It was, however, completely converted to a single metabolite, 7-hydroxy-8-methoxyflavone (7) by Aspergillus flavus. 5-Methoxyflavone (8), when fermented with Beauveria bassiana, gave a single product, 5-methoxyflavanone (9). Conversion of 8 with Aspergillus alliaceus yielded the metabolite 4'-hydroxy-5-methoxyflavone (10). The structures of the compounds 2-7, 9 and 10 were established by spectroscopic methods.
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Herath W., Rakel Mikell J. Microbial metabolism. Part 10: Metabolites of 7,8-dimethoxyflavone and 5-methoxyflavone // Natural Product Research. 2009. Vol. 23. No. 13. pp. 1231-1239.
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Herath W., Rakel Mikell J. Microbial metabolism. Part 10: Metabolites of 7,8-dimethoxyflavone and 5-methoxyflavone // Natural Product Research. 2009. Vol. 23. No. 13. pp. 1231-1239.
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TY - JOUR
DO - 10.1080/14786410902829797
UR - https://doi.org/10.1080/14786410902829797
TI - Microbial metabolism. Part 10: Metabolites of 7,8-dimethoxyflavone and 5-methoxyflavone
T2 - Natural Product Research
AU - Herath, Wimal
AU - Rakel Mikell, Julie
PY - 2009
DA - 2009/09/10
PB - Taylor & Francis
SP - 1231-1239
IS - 13
VL - 23
PMID - 19731142
SN - 1478-6419
SN - 1478-6427
ER -
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BibTex (up to 50 authors)
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@article{2009_Herath,
author = {Wimal Herath and Julie Rakel Mikell},
title = {Microbial metabolism. Part 10: Metabolites of 7,8-dimethoxyflavone and 5-methoxyflavone},
journal = {Natural Product Research},
year = {2009},
volume = {23},
publisher = {Taylor & Francis},
month = {sep},
url = {https://doi.org/10.1080/14786410902829797},
number = {13},
pages = {1231--1239},
doi = {10.1080/14786410902829797}
}
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MLA
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Herath, Wimal, et al. “Microbial metabolism. Part 10: Metabolites of 7,8-dimethoxyflavone and 5-methoxyflavone.” Natural Product Research, vol. 23, no. 13, Sep. 2009, pp. 1231-1239. https://doi.org/10.1080/14786410902829797.