volume 30 issue 24 pages 2845-2849

Protective activity of an anthocyanin-rich extract from bilberries and blackcurrants on acute acetaminophen-induced hepatotoxicity in rats

Mariateresa Cristani 1
Antonio Speciale 1
Ferdinando Mancari 1
T Arcoraci 1
D Ferrari 1
Deborah Fratantonio 1
A. Saija 1
Francesco Cimino 1
Domenico Trombetta 1
Publication typeJournal Article
Publication date2016-03-21
scimago Q2
wos Q3
SJR0.398
CiteScore5.2
Impact factor1.6
ISSN14786419, 14786427
Organic Chemistry
Biochemistry
Plant Science
Analytical Chemistry
Abstract
Acetaminophen (N-acetyl-p-aminophenol, APAP) overdosage can produce fatal centrilobular hepatic necrosis in humans. The present study attempted to investigate the protective effect of an anthocyanin-rich extract from bilberries and blackcurrants (AE) against APAP-induced acute hepatic damage in rats. Treatment with AE normalised blood activities of glutamate oxaloacetate and glutamate pyruvate transaminase and prevented APAP-induced plasmatic and tissutal alterations in biomarkers of oxidative stress, probably due to various bioproperties of the components of the extract.
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GOST Copy
Cristani M. et al. Protective activity of an anthocyanin-rich extract from bilberries and blackcurrants on acute acetaminophen-induced hepatotoxicity in rats // Natural Product Research. 2016. Vol. 30. No. 24. pp. 2845-2849.
GOST all authors (up to 50) Copy
Cristani M., Speciale A., Mancari F., Arcoraci T., Ferrari D., Fratantonio D., Saija A., Cimino F., Trombetta D. Protective activity of an anthocyanin-rich extract from bilberries and blackcurrants on acute acetaminophen-induced hepatotoxicity in rats // Natural Product Research. 2016. Vol. 30. No. 24. pp. 2845-2849.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1080/14786419.2016.1160235
UR - https://doi.org/10.1080/14786419.2016.1160235
TI - Protective activity of an anthocyanin-rich extract from bilberries and blackcurrants on acute acetaminophen-induced hepatotoxicity in rats
T2 - Natural Product Research
AU - Cristani, Mariateresa
AU - Speciale, Antonio
AU - Mancari, Ferdinando
AU - Arcoraci, T
AU - Ferrari, D
AU - Fratantonio, Deborah
AU - Saija, A.
AU - Cimino, Francesco
AU - Trombetta, Domenico
PY - 2016
DA - 2016/03/21
PB - Taylor & Francis
SP - 2845-2849
IS - 24
VL - 30
PMID - 26998559
SN - 1478-6419
SN - 1478-6427
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2016_Cristani,
author = {Mariateresa Cristani and Antonio Speciale and Ferdinando Mancari and T Arcoraci and D Ferrari and Deborah Fratantonio and A. Saija and Francesco Cimino and Domenico Trombetta},
title = {Protective activity of an anthocyanin-rich extract from bilberries and blackcurrants on acute acetaminophen-induced hepatotoxicity in rats},
journal = {Natural Product Research},
year = {2016},
volume = {30},
publisher = {Taylor & Francis},
month = {mar},
url = {https://doi.org/10.1080/14786419.2016.1160235},
number = {24},
pages = {2845--2849},
doi = {10.1080/14786419.2016.1160235}
}
MLA
Cite this
MLA Copy
Cristani, Mariateresa, et al. “Protective activity of an anthocyanin-rich extract from bilberries and blackcurrants on acute acetaminophen-induced hepatotoxicity in rats.” Natural Product Research, vol. 30, no. 24, Mar. 2016, pp. 2845-2849. https://doi.org/10.1080/14786419.2016.1160235.