Open Access
Journal of Dermatological Treatment, volume 28, issue 8, pages 766-773
Topical use of dexpanthenol: a 70th anniversary article
2
Bayer Consumer Care AG, Basel, Switzerland
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Publication type: Journal Article
Publication date: 2017-05-14
Journal:
Journal of Dermatological Treatment
Quartile SCImago
Q1
Quartile WOS
Q2
Impact factor: 2.9
ISSN: 09546634, 14711753
Dermatology
Abstract
Approximately 70 years ago, the first topical dexpanthenol-containing formulation (Bepanthen™ Ointment) has been developed. Nowadays, various topical dexpanthenol preparations exist, tailored according to individual requirements. Topical dexpanthenol has emerged as frequently used formulation in the field of dermatology and skin care. Various studies confirmed dexpanthenol's moisturizing and skin barrier enhancing potential. It prevents skin irritation, stimulates skin regeneration and promotes wound healing. Two main directions in the use of topical dexpanthenol-containing formulations have therefore been pursued: as skin moisturizer/skin barrier restorer and as facilitator of wound healing. This 70th anniversary paper reviews studies with topical dexpanthenol in skin conditions where it is most frequently used. Although discovered decades ago, the exact mechanisms of action of dexpanthenol have not been fully elucidated yet. With the adoption of new technologies, new light has been shed on dexpanthenol's mode of action at the molecular level. It appears that dexpanthenol increases the mobility of stratum corneum molecular components which are important for barrier function and modulates the expression of genes important for wound healing. This review will update readers on recent advances in this field.
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Proksch E. et al. Topical use of dexpanthenol: a 70th anniversary article // Journal of Dermatological Treatment. 2017. Vol. 28. No. 8. pp. 766-773.
GOST all authors (up to 50)
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Proksch E., De Bony R., Trapp S., Boudon S. Topical use of dexpanthenol: a 70th anniversary article // Journal of Dermatological Treatment. 2017. Vol. 28. No. 8. pp. 766-773.
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TY - JOUR
DO - 10.1080/09546634.2017.1325310
UR - https://www.tandfonline.com/doi/full/10.1080/09546634.2017.1325310
TI - Topical use of dexpanthenol: a 70th anniversary article
T2 - Journal of Dermatological Treatment
AU - De Bony, Raymond
AU - Trapp, Sonja
AU - Boudon, Stéphanie
AU - Proksch, Ehrhardt
PY - 2017
DA - 2017/05/14 00:00:00
PB - Taylor & Francis
SP - 766-773
IS - 8
VL - 28
SN - 0954-6634
SN - 1471-1753
ER -
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@article{2017_Proksch,
author = {Raymond De Bony and Sonja Trapp and Stéphanie Boudon and Ehrhardt Proksch},
title = {Topical use of dexpanthenol: a 70th anniversary article},
journal = {Journal of Dermatological Treatment},
year = {2017},
volume = {28},
publisher = {Taylor & Francis},
month = {may},
url = {https://www.tandfonline.com/doi/full/10.1080/09546634.2017.1325310},
number = {8},
pages = {766--773},
doi = {10.1080/09546634.2017.1325310}
}
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MLA
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Proksch, Ehrhardt, et al. “Topical use of dexpanthenol: a 70th anniversary article.” Journal of Dermatological Treatment, vol. 28, no. 8, May. 2017, pp. 766-773. https://www.tandfonline.com/doi/full/10.1080/09546634.2017.1325310.