The Discovery of the Bone-Active Agent Risedronate, and Bisphosphonate Structure-Activity Considerations Including the Aminophenylethane Phosphonate Series
Тип публикации: Journal Article
Дата публикации: 1999-01-01
SCImago Q4
WOS Q3
БС3
SJR: 0.213
CiteScore: 2.6
Impact factor: 1.6
ISSN: 10426507, 15635325, 10267719
Organic Chemistry
Biochemistry
Inorganic Chemistry
Краткое описание
Risedronate was selected for clinical development from a library of more than 200 bisphosphonate analogs for the treatment of a variety of bone diseases. It is a pyridinyl bisphosphonate and is therefore characterized by a nitrogen residue in its structure. Our studies have increased the understanding of the optimal spatial arrangement of the nitrogen and phosphonate moieties required to give the bisphosphonate molecules the geometry necessary for potent antiresorptive activity on bone. A series of aminophenylethane phosphonates have been studied to further demonstrate these geometric requirements.
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ГОСТ
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Ebetino F. H. The Discovery of the Bone-Active Agent Risedronate, and Bisphosphonate Structure-Activity Considerations Including the Aminophenylethane Phosphonate Series // Phosphorus, Sulfur and Silicon and the Related Elements. 1999. Vol. 144. No. 1. pp. 9-12.
ГОСТ со всеми авторами (до 50)
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Ebetino F. H. The Discovery of the Bone-Active Agent Risedronate, and Bisphosphonate Structure-Activity Considerations Including the Aminophenylethane Phosphonate Series // Phosphorus, Sulfur and Silicon and the Related Elements. 1999. Vol. 144. No. 1. pp. 9-12.
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RIS
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TY - JOUR
DO - 10.1080/10426509908546169
UR - https://doi.org/10.1080/10426509908546169
TI - The Discovery of the Bone-Active Agent Risedronate, and Bisphosphonate Structure-Activity Considerations Including the Aminophenylethane Phosphonate Series
T2 - Phosphorus, Sulfur and Silicon and the Related Elements
AU - Ebetino, Frank H.
PY - 1999
DA - 1999/01/01
PB - Taylor & Francis
SP - 9-12
IS - 1
VL - 144
SN - 1042-6507
SN - 1563-5325
SN - 1026-7719
ER -
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BibTex (до 50 авторов)
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@article{1999_Ebetino,
author = {Frank H. Ebetino},
title = {The Discovery of the Bone-Active Agent Risedronate, and Bisphosphonate Structure-Activity Considerations Including the Aminophenylethane Phosphonate Series},
journal = {Phosphorus, Sulfur and Silicon and the Related Elements},
year = {1999},
volume = {144},
publisher = {Taylor & Francis},
month = {jan},
url = {https://doi.org/10.1080/10426509908546169},
number = {1},
pages = {9--12},
doi = {10.1080/10426509908546169}
}
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MLA
Скопировать
Ebetino, Frank H.. “The Discovery of the Bone-Active Agent Risedronate, and Bisphosphonate Structure-Activity Considerations Including the Aminophenylethane Phosphonate Series.” Phosphorus, Sulfur and Silicon and the Related Elements, vol. 144, no. 1, Jan. 1999, pp. 9-12. https://doi.org/10.1080/10426509908546169.
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