Azo dyes and human health: A review
Publication type: Journal Article
Publication date: 2016-09-16
SJR: —
CiteScore: —
Impact factor: —
ISSN: 10590501, 15324095
PubMed ID:
27635691
Cancer Research
Health, Toxicology and Mutagenesis
Abstract
ABSTRACT Synthetic azo dyes are widely used in industries. Gerhardt Domagk discovered that the antimicrobial effect of red azo dye Prontosil was caused by the reductively cleaved (azo reduction) product sulfanilamide. The significance of azo reduction is thus revealed. Azo reduction can be accomplished by human intestinal microflora, skin microflora, environmental microorganisms, to a lesser extent by human liver azoreductase, and by nonbiological means. Some azo dyes can be carcinogenic without being cleaved into aromatic amines. However, the carcinogenicity of many azo dyes is due to their cleaved product such as benzidine. Benzidine induces various human and animal tumors. Another azo dye component, p-phenylenediamine, is a contact allergen. Many azo dyes and their reductively cleaved products as well as chemically related aromatic amines are reported to affect human health, causing allergies and other human maladies.
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Metrics
782
Total citations:
782
Citations from 2025:
108
(13.86%)
Cite this
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GOST
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Chung K. Azo dyes and human health: A review // Environmental Carcinogenesis and Ecotoxicology Reviews. 2016. Vol. 34. No. 4. pp. 233-261.
GOST all authors (up to 50)
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Chung K. Azo dyes and human health: A review // Environmental Carcinogenesis and Ecotoxicology Reviews. 2016. Vol. 34. No. 4. pp. 233-261.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1080/10590501.2016.1236602
UR - https://doi.org/10.1080/10590501.2016.1236602
TI - Azo dyes and human health: A review
T2 - Environmental Carcinogenesis and Ecotoxicology Reviews
AU - Chung, King-Thom
PY - 2016
DA - 2016/09/16
PB - Taylor & Francis
SP - 233-261
IS - 4
VL - 34
PMID - 27635691
SN - 1059-0501
SN - 1532-4095
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2016_Chung,
author = {King-Thom Chung},
title = {Azo dyes and human health: A review},
journal = {Environmental Carcinogenesis and Ecotoxicology Reviews},
year = {2016},
volume = {34},
publisher = {Taylor & Francis},
month = {sep},
url = {https://doi.org/10.1080/10590501.2016.1236602},
number = {4},
pages = {233--261},
doi = {10.1080/10590501.2016.1236602}
}
Cite this
MLA
Copy
Chung, King-Thom. “Azo dyes and human health: A review.” Environmental Carcinogenesis and Ecotoxicology Reviews, vol. 34, no. 4, Sep. 2016, pp. 233-261. https://doi.org/10.1080/10590501.2016.1236602.