Nucleosides, Nucleotides and Nucleic Acids, volume 20, issue 9, pages 1691-1704
SYNTHESIS OF CERTAIN 2′-DEOXYURIDINE DERIVATIVES CONTAINING SUBSTITUTED PHENOXY GROUPS ATTACHED TO C-5′; EVALUATION AS POTENTIAL dUTP ANALOGUES
1
a Cancer Research Campaign Centre for Cancer Therapeutics at the Institute of Cancer Research , 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK
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2
b Cancer Research Campaign Centre for Cancer Therapeutics at the Institute of Cancer Research , 15 Cotswold Road, Sutton, Surrey, SM2 5NG, UK
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Publication type: Journal Article
Publication date: 2001-09-30
Quartile SCImago
Q3
Quartile WOS
Q4
SJR: 0.262
CiteScore: 2.6
Impact factor: 1.1
ISSN: 15257770, 15322335
Biochemistry
General Medicine
Genetics
Molecular Medicine
Abstract
Derivatives of 2'-deoxyuridine in which the 5'-OH group is replaced by a 2,3,6-trifluoro-5-hydroxy-4-nitrophenoxy or a 4-carboxy-2,3,6-trifluoro-5-hydroxyphenoxy group have been prepared for evaluation as possible dUTP analogues. They showed a weak ability to displace radiolabelled dUTP from a dUTP-binding antiserum. The corresponding compounds lacking the three fluorine substituents were prepared for comparison.
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Marriott J. H. et al. SYNTHESIS OF CERTAIN 2′-DEOXYURIDINE DERIVATIVES CONTAINING SUBSTITUTED PHENOXY GROUPS ATTACHED TO C-5′; EVALUATION AS POTENTIAL dUTP ANALOGUES // Nucleosides, Nucleotides and Nucleic Acids. 2001. Vol. 20. No. 9. pp. 1691-1704.
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Marriott J. H., AHERNE G. W., Hardcastle A., JARMAN M. SYNTHESIS OF CERTAIN 2′-DEOXYURIDINE DERIVATIVES CONTAINING SUBSTITUTED PHENOXY GROUPS ATTACHED TO C-5′; EVALUATION AS POTENTIAL dUTP ANALOGUES // Nucleosides, Nucleotides and Nucleic Acids. 2001. Vol. 20. No. 9. pp. 1691-1704.
Cite this
RIS
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TY - JOUR
DO - 10.1081/ncn-100105905
UR - https://doi.org/10.1081/ncn-100105905
TI - SYNTHESIS OF CERTAIN 2′-DEOXYURIDINE DERIVATIVES CONTAINING SUBSTITUTED PHENOXY GROUPS ATTACHED TO C-5′; EVALUATION AS POTENTIAL dUTP ANALOGUES
T2 - Nucleosides, Nucleotides and Nucleic Acids
AU - Marriott, Jonathan H
AU - AHERNE, G. WYNNE
AU - Hardcastle, Anthea
AU - JARMAN, MICHAEL
PY - 2001
DA - 2001/09/30
PB - Taylor & Francis
SP - 1691-1704
IS - 9
VL - 20
SN - 1525-7770
SN - 1532-2335
ER -
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@article{2001_Marriott,
author = {Jonathan H Marriott and G. WYNNE AHERNE and Anthea Hardcastle and MICHAEL JARMAN},
title = {SYNTHESIS OF CERTAIN 2′-DEOXYURIDINE DERIVATIVES CONTAINING SUBSTITUTED PHENOXY GROUPS ATTACHED TO C-5′; EVALUATION AS POTENTIAL dUTP ANALOGUES},
journal = {Nucleosides, Nucleotides and Nucleic Acids},
year = {2001},
volume = {20},
publisher = {Taylor & Francis},
month = {sep},
url = {https://doi.org/10.1081/ncn-100105905},
number = {9},
pages = {1691--1704},
doi = {10.1081/ncn-100105905}
}
Cite this
MLA
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Marriott, Jonathan H., et al. “SYNTHESIS OF CERTAIN 2′-DEOXYURIDINE DERIVATIVES CONTAINING SUBSTITUTED PHENOXY GROUPS ATTACHED TO C-5′; EVALUATION AS POTENTIAL dUTP ANALOGUES.” Nucleosides, Nucleotides and Nucleic Acids, vol. 20, no. 9, Sep. 2001, pp. 1691-1704. https://doi.org/10.1081/ncn-100105905.