Reactivity Models of 1-N-Vinyluracil and Synthesis of a New Class of Potential Antiviral Agents by the Use of 1,3-Dipolar Cycloaddition Reactions
Evelina Colacino
1, 2
,
G De Luca
3
,
Angelo Liguori
3
,
Anna Napoli
3
,
Carlo Siciliano
3
,
Giovanni Sindona
3
Publication type: Journal Article
Publication date: 2003-10-01
scimago Q3
wos Q4
SJR: 0.312
CiteScore: 2.1
Impact factor: 1.3
ISSN: 15257770, 15322335
PubMed ID:
14565268
Biochemistry
General Medicine
Genetics
Molecular Medicine
Abstract
By the use of a convergent approach based on 1,3-dipolar cycloaddition reactions between N-protected formylnitrones generated in situ and 1-N-vinyluracil, a new class of 4'-aza-analogues of 2',3'-dideoxynucleosides is synthesized. Competitive reaction for the endocyclic bond of uracil also brings to a new isoxazolidine derivative fused with the pyrimidine nucleus.
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Colacino E. et al. Reactivity Models of 1-N-Vinyluracil and Synthesis of a New Class of Potential Antiviral Agents by the Use of 1,3-Dipolar Cycloaddition Reactions // Nucleosides, Nucleotides and Nucleic Acids. 2003. Vol. 22. No. 5-8. pp. 743-745.
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Colacino E., De Luca G., Liguori A., Napoli A., Siciliano C., Sindona G. Reactivity Models of 1-N-Vinyluracil and Synthesis of a New Class of Potential Antiviral Agents by the Use of 1,3-Dipolar Cycloaddition Reactions // Nucleosides, Nucleotides and Nucleic Acids. 2003. Vol. 22. No. 5-8. pp. 743-745.
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RIS
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TY - JOUR
DO - 10.1081/ncn-120022624
UR - https://doi.org/10.1081/ncn-120022624
TI - Reactivity Models of 1-N-Vinyluracil and Synthesis of a New Class of Potential Antiviral Agents by the Use of 1,3-Dipolar Cycloaddition Reactions
T2 - Nucleosides, Nucleotides and Nucleic Acids
AU - Colacino, Evelina
AU - De Luca, G
AU - Liguori, Angelo
AU - Napoli, Anna
AU - Siciliano, Carlo
AU - Sindona, Giovanni
PY - 2003
DA - 2003/10/01
PB - Taylor & Francis
SP - 743-745
IS - 5-8
VL - 22
PMID - 14565268
SN - 1525-7770
SN - 1532-2335
ER -
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BibTex (up to 50 authors)
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@article{2003_Colacino,
author = {Evelina Colacino and G De Luca and Angelo Liguori and Anna Napoli and Carlo Siciliano and Giovanni Sindona},
title = {Reactivity Models of 1-N-Vinyluracil and Synthesis of a New Class of Potential Antiviral Agents by the Use of 1,3-Dipolar Cycloaddition Reactions},
journal = {Nucleosides, Nucleotides and Nucleic Acids},
year = {2003},
volume = {22},
publisher = {Taylor & Francis},
month = {oct},
url = {https://doi.org/10.1081/ncn-120022624},
number = {5-8},
pages = {743--745},
doi = {10.1081/ncn-120022624}
}
Cite this
MLA
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Colacino, Evelina, et al. “Reactivity Models of 1-N-Vinyluracil and Synthesis of a New Class of Potential Antiviral Agents by the Use of 1,3-Dipolar Cycloaddition Reactions.” Nucleosides, Nucleotides and Nucleic Acids, vol. 22, no. 5-8, Oct. 2003, pp. 743-745. https://doi.org/10.1081/ncn-120022624.