Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy
Publication type: Journal Article
Publication date: 2018-08-21
scimago Q3
wos Q3
SJR: 0.324
CiteScore: 3.0
Impact factor: 1.4
ISSN: 16122011, 1612202X
Physics and Astronomy (miscellaneous)
Instrumentation
Abstract
Modern fluorescent modalities play an important role in the functional diagnostic of various physiological processes in living tissues. Utilizing the fluorescence spectroscopy approach we observe the circulation of fluorescent-labelled nanocapsules with rhodamine tetramethylrhodamine in a microcirculatory blood system. The measurements were conducted transcutaneously on the surface of healthy Wistar rat thighs in vivo. The administration of the preparation capsule suspension with a rhodamine concentration of 5 mg kg−1 of the animal weight resulted in a two-fold increase of fluorescence intensity relative to the baseline level. The dissemination of nanocapsules in the adjacent tissues via the circulatory system was observed and assessed quantitatively. The approach can be used for the transdermal assessment of rhodamine-loaded capsules in vivo.
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Tarakanchikova Y. et al. Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy // Laser Physics Letters. 2018. Vol. 15. No. 10. p. 105601.
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Tarakanchikova Y., Stelmashchuk O., Seryogina E., Piavchenko G., Zherebtsov E., Dunaev A., Popov A., MEGLINSKI I. Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy // Laser Physics Letters. 2018. Vol. 15. No. 10. p. 105601.
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RIS
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TY - JOUR
DO - 10.1088/1612-202X/aad857
UR - https://iopscience.iop.org/article/10.1088/1612-202X/aad857
TI - Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy
T2 - Laser Physics Letters
AU - Tarakanchikova, Yana
AU - Stelmashchuk, Olga
AU - Seryogina, Evgeniya
AU - Piavchenko, Gennadii
AU - Zherebtsov, Evgeny
AU - Dunaev, Andrey
AU - Popov, Alexey
AU - MEGLINSKI, IGOR
PY - 2018
DA - 2018/08/21
PB - IOP Publishing
SP - 105601
IS - 10
VL - 15
SN - 1612-2011
SN - 1612-202X
ER -
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@article{2018_Tarakanchikova,
author = {Yana Tarakanchikova and Olga Stelmashchuk and Evgeniya Seryogina and Gennadii Piavchenko and Evgeny Zherebtsov and Andrey Dunaev and Alexey Popov and IGOR MEGLINSKI},
title = {Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy},
journal = {Laser Physics Letters},
year = {2018},
volume = {15},
publisher = {IOP Publishing},
month = {aug},
url = {https://iopscience.iop.org/article/10.1088/1612-202X/aad857},
number = {10},
pages = {105601},
doi = {10.1088/1612-202X/aad857}
}
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MLA
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Tarakanchikova, Yana, et al. “Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy.” Laser Physics Letters, vol. 15, no. 10, Aug. 2018, p. 105601. https://iopscience.iop.org/article/10.1088/1612-202X/aad857.