Laser Physics Letters, volume 15, issue 10, pages 105601

Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy

Publication typeJournal Article
Publication date2018-08-21
Quartile SCImago
Q2
Quartile WOS
Q3
Impact factor1.7
ISSN16122011, 1612202X
Physics and Astronomy (miscellaneous)
Instrumentation
Abstract
Modern fluorescent modalities play an important role in the functional diagnostic of various physiological processes in living tissues. Utilizing the fluorescence spectroscopy approach we observe the circulation of fluorescent-labelled nanocapsules with rhodamine tetramethylrhodamine in a microcirculatory blood system. The measurements were conducted transcutaneously on the surface of healthy Wistar rat thighs in vivo. The administration of the preparation capsule suspension with a rhodamine concentration of 5 mg kg−1 of the animal weight resulted in a two-fold increase of fluorescence intensity relative to the baseline level. The dissemination of nanocapsules in the adjacent tissues via the circulatory system was observed and assessed quantitatively. The approach can be used for the transdermal assessment of rhodamine-loaded capsules in vivo.

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Stelmashchuk O. et al. Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy // Laser Physics Letters. 2018. Vol. 15. No. 10. p. 105601.
GOST all authors (up to 50) Copy
Stelmashchuk O., Seryogina E., Piavchenko G., Zherebtsov E., Dunaev A., Popov A., MEGLINSKI I., Tarakanchikova Y. Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy // Laser Physics Letters. 2018. Vol. 15. No. 10. p. 105601.
RIS |
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RIS Copy
TY - JOUR
DO - 10.1088/1612-202X/aad857
UR - https://doi.org/10.1088%2F1612-202X%2Faad857
TI - Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy
T2 - Laser Physics Letters
AU - Stelmashchuk, Olga
AU - Seryogina, Evgeniya
AU - Piavchenko, Gennadii
AU - Zherebtsov, Evgeny
AU - Dunaev, Andrey
AU - Popov, Alexey
AU - MEGLINSKI, IGOR
AU - Tarakanchikova, Yana
PY - 2018
DA - 2018/08/21 00:00:00
PB - IOP Publishing
SP - 105601
IS - 10
VL - 15
SN - 1612-2011
SN - 1612-202X
ER -
BibTex |
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BibTex Copy
@article{2018_Stelmashchuk
author = {Olga Stelmashchuk and Evgeniya Seryogina and Gennadii Piavchenko and Evgeny Zherebtsov and Andrey Dunaev and Alexey Popov and IGOR MEGLINSKI and Yana Tarakanchikova},
title = {Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy},
journal = {Laser Physics Letters},
year = {2018},
volume = {15},
publisher = {IOP Publishing},
month = {aug},
url = {https://doi.org/10.1088%2F1612-202X%2Faad857},
number = {10},
pages = {105601},
doi = {10.1088/1612-202X/aad857}
}
MLA
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MLA Copy
Stelmashchuk, Olga, et al. “Allocation of rhodamine-loaded nanocapsules from blood circulatory system to adjacent tissues assessed in vivo by fluorescence spectroscopy.” Laser Physics Letters, vol. 15, no. 10, Aug. 2018, p. 105601. https://doi.org/10.1088%2F1612-202X%2Faad857.
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