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Journal of Physics: Conference Series, volume 1389, issue 1, pages 12071

Superparamagnetic nanopreparations in early diagnostics and treatment of cancer

Brusentsov N.A. 1
, 
Polyanskiy Va 2
, 
Golubeva I S 1
, 
Baryshnikova M A 1
, 
Barmashov A E 1
, 
Bukreyev Yu M 1
, 
Bocharova O. A. 1
, 
Gulyayev M V 3
, 
Pirogov Yu A 3
, 
Anisimov N V 3
1
 
2
 
3
 
Publication type: Journal Article
Publication date: 2019-11-01
Quartile SCImago
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ISSN: 17426588, 17426596
General Physics and Astronomy
Abstract

The superparamagnetic nanoparticles of magnetite citrate (SNMCs) consisting of nanospheres aggregates with the hydrodynamic diameter being between 15 to 35 nm with a magnetite core diameter of 3 to 12 nm, coated with of citrate anions was synthesized. A water 2-5% sol of SNMC was successfully tested as magnetic resonance imaging (MRI) contrast agent. The same 40% sol was then combined with Inox and used at regional magneto-thermo-chemo-therapy (RMTCT) of Lewis lung carcinoma (LLC) and Ehrlich carcinoma (EC), in female C57Bl / 6j mice. In the early stages of carcinoma development, the proliferation centers of LLC and EC cells were visualized and, during treatment, they obtained a significant increase in the efficiency of regional magneto-thermo-chemo-therapy.

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Brusentsov N. et al. Superparamagnetic nanopreparations in early diagnostics and treatment of cancer // Journal of Physics: Conference Series. 2019. Vol. 1389. No. 1. p. 12071.
GOST all authors (up to 50) Copy
Brusentsov N., Polyanskiy V., Golubeva I. S., Baryshnikova M. A., Barmashov A. E., Bukreyev Yu. M., Bocharova O. A., Gulyayev M. V., Pirogov Yu. A., Anisimov N. V. Superparamagnetic nanopreparations in early diagnostics and treatment of cancer // Journal of Physics: Conference Series. 2019. Vol. 1389. No. 1. p. 12071.
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TY - JOUR
DO - 10.1088/1742-6596/1389/1/012071
UR - https://doi.org/10.1088%2F1742-6596%2F1389%2F1%2F012071
TI - Superparamagnetic nanopreparations in early diagnostics and treatment of cancer
T2 - Journal of Physics: Conference Series
AU - Brusentsov, N.A.
AU - Polyanskiy, Va
AU - Golubeva, I S
AU - Baryshnikova, M A
AU - Barmashov, A E
AU - Bukreyev, Yu M
AU - Bocharova, O. A.
AU - Gulyayev, M V
AU - Pirogov, Yu A
AU - Anisimov, N V
PY - 2019
DA - 2019/11/01 00:00:00
PB - IOP Publishing
SP - 12071
IS - 1
VL - 1389
SN - 1742-6588
SN - 1742-6596
ER -
BibTex |
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@article{2019_Brusentsov,
author = {N.A. Brusentsov and Va Polyanskiy and I S Golubeva and M A Baryshnikova and A E Barmashov and Yu M Bukreyev and O. A. Bocharova and M V Gulyayev and Yu A Pirogov and N V Anisimov},
title = {Superparamagnetic nanopreparations in early diagnostics and treatment of cancer},
journal = {Journal of Physics: Conference Series},
year = {2019},
volume = {1389},
publisher = {IOP Publishing},
month = {nov},
url = {https://doi.org/10.1088%2F1742-6596%2F1389%2F1%2F012071},
number = {1},
pages = {12071},
doi = {10.1088/1742-6596/1389/1/012071}
}
MLA
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MLA Copy
Brusentsov, N.A., et al. “Superparamagnetic nanopreparations in early diagnostics and treatment of cancer.” Journal of Physics: Conference Series, vol. 1389, no. 1, Nov. 2019, p. 12071. https://doi.org/10.1088%2F1742-6596%2F1389%2F1%2F012071.
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