Open Access
Chitosan-g-lactide copolymers for fabrication of 3D scaffolds for tissue engineering
Tatiana Demina
1
,
Daria S Zaytseva Zotova
2
,
Petr S. Timashev
3
,
V. N. Bagratashvili
3
,
Ch Sevrin
4
,
N.M. Surin
1
,
E. Markvicheva
2
,
C. Grandfils
5
,
Publication type: Journal Article
Publication date: 2015-07-16
SJR: —
CiteScore: —
Impact factor: —
ISSN: 17578981, 1757899X
General Medicine
Abstract
Chitosan-g-oligo (L, D-lactide) copolymers were synthesized and assessed to fabricate a number of 3D scaffolds using a variety of technologies such as oil/water emulsion evaporation technique, freeze-drying and two-photon photopolymerization. Solid-state copolymerization method allowed us to graft up to 160 wt-% of oligolactide onto chitosan backbone via chitosan amino group acetylation with substitution degree reaching up to 0.41. Grafting of hydrophobic oligolactide side chains with polymerization degree up to 10 results in chitosan amphiphilic properties. The synthesized chitosan-g-lactide copolymers were used to design 3D scaffolds for tissue engineering such as spherical microparticles and macroporous hydrogels.
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Demina T. S. et al. Chitosan-g-lactide copolymers for fabrication of 3D scaffolds for tissue engineering // IOP Conference Series: Materials Science and Engineering. 2015. Vol. 87. No. 1. p. 12074.
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Demina T., Zaytseva Zotova D. S., Timashev P. S., Bagratashvili V. N., Bardakova K. N., Sevrin C., Svidchenko E. A., Surin N., Markvicheva E., Grandfils C., Akopova T. Chitosan-g-lactide copolymers for fabrication of 3D scaffolds for tissue engineering // IOP Conference Series: Materials Science and Engineering. 2015. Vol. 87. No. 1. p. 12074.
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RIS
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TY - JOUR
DO - 10.1088/1757-899X/87/1/012074
UR - https://doi.org/10.1088/1757-899X/87/1/012074
TI - Chitosan-g-lactide copolymers for fabrication of 3D scaffolds for tissue engineering
T2 - IOP Conference Series: Materials Science and Engineering
AU - Demina, Tatiana
AU - Zaytseva Zotova, Daria S
AU - Timashev, Petr S.
AU - Bagratashvili, V. N.
AU - Bardakova, Kseniia N.
AU - Sevrin, Ch
AU - Svidchenko, Evgeniya A.
AU - Surin, N.M.
AU - Markvicheva, E.
AU - Grandfils, C.
AU - Akopova, Tatiana
PY - 2015
DA - 2015/07/16
PB - IOP Publishing
SP - 12074
IS - 1
VL - 87
SN - 1757-8981
SN - 1757-899X
ER -
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BibTex (up to 50 authors)
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@article{2015_Demina,
author = {Tatiana Demina and Daria S Zaytseva Zotova and Petr S. Timashev and V. N. Bagratashvili and Kseniia N. Bardakova and Ch Sevrin and Evgeniya A. Svidchenko and N.M. Surin and E. Markvicheva and C. Grandfils and Tatiana Akopova},
title = {Chitosan-g-lactide copolymers for fabrication of 3D scaffolds for tissue engineering},
journal = {IOP Conference Series: Materials Science and Engineering},
year = {2015},
volume = {87},
publisher = {IOP Publishing},
month = {jul},
url = {https://doi.org/10.1088/1757-899X/87/1/012074},
number = {1},
pages = {12074},
doi = {10.1088/1757-899X/87/1/012074}
}
Cite this
MLA
Copy
Demina, T. S., et al. “Chitosan-g-lactide copolymers for fabrication of 3D scaffolds for tissue engineering.” IOP Conference Series: Materials Science and Engineering, vol. 87, no. 1, Jul. 2015, p. 12074. https://doi.org/10.1088/1757-899X/87/1/012074.