Effects of N-Nitropyrazoles on Ocular Blood Flow of Rabbits and Retinal Function Recovery of Rat Eyes after Ischemic Insults
Тип публикации: Journal Article
Дата публикации: 2002-07-26
scimago Q2
wos Q2
БС1
SJR: 0.597
CiteScore: 3.5
Impact factor: 2.1
ISSN: 10807683, 15577732
PubMed ID:
11777174
Pharmacology
Pharmacology (medical)
Ophthalmology
Краткое описание
Twelve compounds of N-nitropyrazoles were studied for their effects on ocular blood flow in rabbits and retinal function recovery in rat eyes after ischemic insults. Of the twelve N-nitropyrazoles examined, nine increased choroidal blood flow while five increased retinal blood flow significantly. On the other hand, all twelve compounds increased blood flow in iris and ciliary muscle without exception. As for retinal function recovery after ischemic insult in rat eyes, eight out of the twelve compounds showed more significant facilitation than the control. The structure activity relationship of the N-nitropyrazoles to increase ocular blood flow and to facilitate retinal function recovery after ischemic insults were discussed.
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Mary Ann Liebert
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Xuan B. et al. Effects of N-Nitropyrazoles on Ocular Blood Flow of Rabbits and Retinal Function Recovery of Rat Eyes after Ischemic Insults // Journal of Ocular Pharmacology and Therapeutics. 2002. Vol. 17. No. 6. pp. 505-515.
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Xuan B., Wang T., Chiou G., Dalinger I., Shkineva T., Shevelev S. Effects of N-Nitropyrazoles on Ocular Blood Flow of Rabbits and Retinal Function Recovery of Rat Eyes after Ischemic Insults // Journal of Ocular Pharmacology and Therapeutics. 2002. Vol. 17. No. 6. pp. 505-515.
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TY - JOUR
DO - 10.1089/10807680152729194
UR - https://doi.org/10.1089/10807680152729194
TI - Effects of N-Nitropyrazoles on Ocular Blood Flow of Rabbits and Retinal Function Recovery of Rat Eyes after Ischemic Insults
T2 - Journal of Ocular Pharmacology and Therapeutics
AU - Xuan, B.
AU - Wang, T
AU - Chiou, G.C.Y.
AU - Dalinger, I.
AU - Shkineva, T.K.
AU - Shevelev, S.A.
PY - 2002
DA - 2002/07/26
PB - Mary Ann Liebert
SP - 505-515
IS - 6
VL - 17
PMID - 11777174
SN - 1080-7683
SN - 1557-7732
ER -
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@article{2002_Xuan,
author = {B. Xuan and T Wang and G.C.Y. Chiou and I. Dalinger and T.K. Shkineva and S.A. Shevelev},
title = {Effects of N-Nitropyrazoles on Ocular Blood Flow of Rabbits and Retinal Function Recovery of Rat Eyes after Ischemic Insults},
journal = {Journal of Ocular Pharmacology and Therapeutics},
year = {2002},
volume = {17},
publisher = {Mary Ann Liebert},
month = {jul},
url = {https://doi.org/10.1089/10807680152729194},
number = {6},
pages = {505--515},
doi = {10.1089/10807680152729194}
}
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MLA
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Xuan, B., et al. “Effects of N-Nitropyrazoles on Ocular Blood Flow of Rabbits and Retinal Function Recovery of Rat Eyes after Ischemic Insults.” Journal of Ocular Pharmacology and Therapeutics, vol. 17, no. 6, Jul. 2002, pp. 505-515. https://doi.org/10.1089/10807680152729194.