,
volume 75
,
issue 9
,
pages 1788-1795
Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study
Tielong Chen
1
,
Zhe Dai
2
,
Pingzheng Mo
1
,
Xinyu Li
3
,
Zhiyong Ma
1
,
Shihui Song
1
,
Xiaoping Chen
1
,
Mingqi Luo
1
,
Ke Liang
1
,
Shicheng Gao
1
,
Yong-Xi Zhang
1
,
Liping Deng
1
,
Yong Xiong
1
Publication type: Journal Article
Publication date: 2020-04-11
scimago Q1
wos Q1
SJR: 1.334
CiteScore: 8.9
Impact factor: 3.8
ISSN: 10795006, 1758535X
PubMed ID:
32279081
Geriatrics and Gerontology
Aging
Abstract
Background
In December 2019, the coronavirus disease 2019 (COVID-19) emerged in Wuhan city and spread rapidly throughout China and the world. In this study, we aimed to describe the clinical course and outcomes of older patients with COVID-19.
Methods
This is a retrospective investigation of hospitalized older patients with confirmed COVID-19 at Zhongnan Hospital of Wuhan University from January 1, 2020, to February 10, 2020.
Results
In total, 203 patients were diagnosed with COVID-19, with a median age of 54 years (interquartile range, 41–68; range, 20–91 years). Men accounted for 108 (53.2%) of the cases, and 55 patients (27.1%) were more than 65 years of age. Among patients who were 65 years and older, the mortality rate was 34.5% (19/55), which was significantly higher than that of the younger patients at 4.7% (7/148). Common symptoms of older patients with COVID-19 included fever (94.5%; n = 52), dry cough (69.1%; n = 38), and chest distress (63.6%; n = 35). Compared with young patients, older patients had more laboratory abnormalities and comorbidities. Through a multivariate analysis of the causes of death in older patients, we found that males, comorbidities, time from disease onset to hospitalization, abnormal kidney function, and elevated procalcitonin levels were all significantly associated with death.
Conclusions
In the recent outbreak of COVID-19, our local hospital in Wuhan found that patients aged 65 and older had greater initial comorbidities, more severe symptoms, and were more likely to experience multiorgan involvement and death, as compared to younger patients.
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Total citations:
281
Citations from 2024:
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(7.48%)
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GOST
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Chen T. et al. Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study // Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2020. Vol. 75. No. 9. pp. 1788-1795.
GOST all authors (up to 50)
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Chen T., Dai Z., Mo P., Li X., Ma Z., Song S., Chen X., Luo M., Liang K., Gao S., Zhang Y., Deng L., Xiong Y. Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study // Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2020. Vol. 75. No. 9. pp. 1788-1795.
Cite this
RIS
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TY - JOUR
DO - 10.1093/gerona/glaa089
UR - https://doi.org/10.1093/gerona/glaa089
TI - Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study
T2 - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
AU - Chen, Tielong
AU - Dai, Zhe
AU - Mo, Pingzheng
AU - Li, Xinyu
AU - Ma, Zhiyong
AU - Song, Shihui
AU - Chen, Xiaoping
AU - Luo, Mingqi
AU - Liang, Ke
AU - Gao, Shicheng
AU - Zhang, Yong-Xi
AU - Deng, Liping
AU - Xiong, Yong
PY - 2020
DA - 2020/04/11
PB - Oxford University Press
SP - 1788-1795
IS - 9
VL - 75
PMID - 32279081
SN - 1079-5006
SN - 1758-535X
ER -
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BibTex (up to 50 authors)
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@article{2020_Chen,
author = {Tielong Chen and Zhe Dai and Pingzheng Mo and Xinyu Li and Zhiyong Ma and Shihui Song and Xiaoping Chen and Mingqi Luo and Ke Liang and Shicheng Gao and Yong-Xi Zhang and Liping Deng and Yong Xiong},
title = {Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study},
journal = {Journals of Gerontology - Series A Biological Sciences and Medical Sciences},
year = {2020},
volume = {75},
publisher = {Oxford University Press},
month = {apr},
url = {https://doi.org/10.1093/gerona/glaa089},
number = {9},
pages = {1788--1795},
doi = {10.1093/gerona/glaa089}
}
Cite this
MLA
Copy
Chen, Tielong, et al. “Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study.” Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 75, no. 9, Apr. 2020, pp. 1788-1795. https://doi.org/10.1093/gerona/glaa089.