Stop COVID Cohort: An Observational Study of 3480 Patients Admitted to the Sechenov University Hospital Network in Moscow City for Suspected Coronavirus Disease 2019 (COVID-19) Infection
Background
The epidemiology, clinical course, and outcomes of COVID-19 patients in the Russian population are unknown. Information on the differences between laboratory-confirmed and clinically-diagnosed COVID-19 in real-life settings is lacking.
Methods
We extracted data from the medical records of adult patients who were consecutively admitted for suspected COVID-19 infection in Moscow, between April 8 and May 28, 2020.
Results
Of the 4261 patients hospitalised for suspected COVID-19, outcomes were available for 3480 patients (median age 56 years (interquartile range 45-66). The commonest comorbidities were hypertension, obesity, chronic cardiac disease and diabetes. Half of the patients (n=1728) had a positive RT-PCR while 1748 were negative on RT-PCR but had clinical symptoms and characteristic CT signs suggestive of COVID-19 infection.No significant differences in frequency of symptoms, laboratory test results and risk factors for in-hospital mortality were found between those exclusively clinically diagnosed or with positive SARS-CoV-2 RT-PCR.In a multivariable logistic regression model the following were associated with in-hospital mortality; older age (per 1 year increase) odds ratio [OR] 1.05 (95% confidence interval (CI) 1.03 - 1.06); male sex (OR 1.71, 1.24 - 2.37); chronic kidney disease (OR 2.99, 1.89 – 4.64); diabetes (OR 2.1, 1.46 - 2.99); chronic cardiac disease (OR 1.78, 1.24 - 2.57) and dementia (OR 2.73, 1.34 – 5.47).
Conclusions
Age, male sex, and chronic comorbidities were risk factors for in-hospital mortality. The combination of clinical features were sufficient to diagnoseCOVID-19 infection indicating that laboratory testing is not critical in real-life clinical practice.
Топ-30
Журналы
|
1
2
|
|
|
Clinical Infectious Diseases
2 публикации, 4.17%
|
|
|
BMC Medicine
2 публикации, 4.17%
|
|
|
Diagnostics
2 публикации, 4.17%
|
|
|
Metabolites
1 публикация, 2.08%
|
|
|
The Lancet Infectious Diseases
1 публикация, 2.08%
|
|
|
Infection
1 публикация, 2.08%
|
|
|
Clinical and Experimental Allergy
1 публикация, 2.08%
|
|
|
European Respiratory Journal
1 публикация, 2.08%
|
|
|
Aging
1 публикация, 2.08%
|
|
|
Current Opinion in Allergy and Clinical Immunology
1 публикация, 2.08%
|
|
|
World Journal of Gastroenterology
1 публикация, 2.08%
|
|
|
Viruses
1 публикация, 2.08%
|
|
|
Frontiers in Immunology
1 публикация, 2.08%
|
|
|
BMC Neurology
1 публикация, 2.08%
|
|
|
Journal of Nephrology
1 публикация, 2.08%
|
|
|
Current Pharmacology Reports
1 публикация, 2.08%
|
|
|
PLOS Global Public Health
1 публикация, 2.08%
|
|
|
The Lancet Regional Health - Europe
1 публикация, 2.08%
|
|
|
Cochrane Database of Systematic Reviews
1 публикация, 2.08%
|
|
|
Pediatric Allergy and Immunology
1 публикация, 2.08%
|
|
|
British Journal of Psychiatry
1 публикация, 2.08%
|
|
|
Leukemia and Lymphoma
1 публикация, 2.08%
|
|
|
Problemy Endokrinologii
1 публикация, 2.08%
|
|
|
BMJ Open
1 публикация, 2.08%
|
|
|
Obshchaya Reanimatologiya
1 публикация, 2.08%
|
|
|
Global Health & Medicine
1 публикация, 2.08%
|
|
|
medRxiv : the preprint server for health sciences
1 публикация, 2.08%
|
|
|
Meditsinskiy sovet = Medical Council
1 публикация, 2.08%
|
|
|
Messenger of Anesthesiology and Resuscitation (Vestnik anesteziologii i reanimatologii)
1 публикация, 2.08%
|
|
|
1
2
|
Издатели
|
1
2
3
4
5
6
7
|
|
|
Springer Nature
7 публикаций, 14.58%
|
|
|
MDPI
6 публикаций, 12.5%
|
|
|
Cold Spring Harbor Laboratory
5 публикаций, 10.42%
|
|
|
Wiley
4 публикации, 8.33%
|
|
|
Elsevier
3 публикации, 6.25%
|
|
|
Oxford University Press
2 публикации, 4.17%
|
|
|
European Respiratory Society (ERS)
1 публикация, 2.08%
|
|
|
Impact Journals
1 публикация, 2.08%
|
|
|
Ovid Technologies (Wolters Kluwer Health)
1 публикация, 2.08%
|
|
|
Baishideng Publishing Group
1 публикация, 2.08%
|
|
|
Frontiers Media S.A.
1 публикация, 2.08%
|
|
|
Public Library of Science (PLoS)
1 публикация, 2.08%
|
|
|
Royal College of Psychiatrists
1 публикация, 2.08%
|
|
|
Taylor & Francis
1 публикация, 2.08%
|
|
|
Endocrinology Research Centre
1 публикация, 2.08%
|
|
|
BMJ
1 публикация, 2.08%
|
|
|
FSBI SRIGR RAMS
1 публикация, 2.08%
|
|
|
National Center for Global Health and Medicine (JST)
1 публикация, 2.08%
|
|
|
Remedium, Ltd.
1 публикация, 2.08%
|
|
|
FSBEI HE I.P. Pavlov SPbSMU MOH Russia
1 публикация, 2.08%
|
|
|
Volgograd State Medical University
1 публикация, 2.08%
|
|
|
Journal of Childrens Infections
1 публикация, 2.08%
|
|
|
Silicea - Poligraf
1 публикация, 2.08%
|
|
|
LLC Numicom
1 публикация, 2.08%
|
|
|
Bentham Science Publishers Ltd.
1 публикация, 2.08%
|
|
|
Media Sphere Publishing House
1 публикация, 2.08%
|
|
|
Eco-Vector LLC
1 публикация, 2.08%
|
|
|
1
2
3
4
5
6
7
|
- Мы не учитываем публикации, у которых нет DOI.
- Статистика публикаций обновляется еженедельно.