Inflammatory Bowel Diseases
Helicobacter pylori and Inflammatory Bowel Disease: An Unresolved Enigma
Juris Pokrotnieks
1, 2
,
Stanislav Sitkin
3, 4, 5
2
Centre of Gastroenterology, Hepatology and Nutrition, Pauls Stradiņš Clinical University Hospital , Riga , Latvia
|
5
R&D Department, Elpis Ltd , Riga , Latvia
|
Publication type: Journal Article
Publication date: 2022-12-14
Journal:
Inflammatory Bowel Diseases
scimago Q1
SJR: 1.550
CiteScore: 9.7
Impact factor: 4.5
ISSN: 10780998, 15364844
Abstract
Lay Summary
The article describes the hypothesis that there may be a noncausal relationship between Helicobacter pylori infection and inflammatory bowel disease (IBD) that is related to the host mucin glycan fucosylation status in the gastrointestinal tract. The proposed hypothesis may explain why IBD is less prevalent in patients with H. pylori, and no increased risk of IBD is seen after H. pylori eradication therapy, as was shown in the study by Tanner et al.
Found
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