Open Access
Nucleic Acids Research, volume 46, issue 16, pages 8038-8056
i-Motif DNA: structural features and significance to cell biology
Publication type: Journal Article
Publication date: 2018-08-16
Journal:
Nucleic Acids Research
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor: 14.9
ISSN: 03051048, 13624962
Genetics
Abstract
The i-motif represents a paradigmatic example of the wide structural versatility of nucleic acids. In remarkable contrast to duplex DNA, i-motifs are four-stranded DNA structures held together by hemi- protonated and intercalated cytosine base pairs (C:C+). First observed 25 years ago, and considered by many as a mere structural oddity, interest in and discussion on the biological role of i-motifs have grown dramatically in recent years. In this review we focus on structural aspects of i-motif formation, the factors leading to its stabilization and recent studies describing the possible role of i-motifs in fundamental biological processes.
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GOST
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Abou Assi H. et al. i-Motif DNA: structural features and significance to cell biology // Nucleic Acids Research. 2018. Vol. 46. No. 16. pp. 8038-8056.
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Abou Assi H., Garavís M., Gonzalez C., Damha M. J. i-Motif DNA: structural features and significance to cell biology // Nucleic Acids Research. 2018. Vol. 46. No. 16. pp. 8038-8056.
Cite this
RIS
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TY - JOUR
DO - 10.1093/nar/gky735
UR - https://doi.org/10.1093/nar/gky735
TI - i-Motif DNA: structural features and significance to cell biology
T2 - Nucleic Acids Research
AU - Abou Assi, Hala
AU - Garavís, Miguel
AU - Gonzalez, Carlos
AU - Damha, Masad J.
PY - 2018
DA - 2018/08/16
PB - Oxford University Press
SP - 8038-8056
IS - 16
VL - 46
SN - 0305-1048
SN - 1362-4962
ER -
Cite this
BibTex
Copy
@article{2018_Abou Assi,
author = {Hala Abou Assi and Miguel Garavís and Carlos Gonzalez and Masad J. Damha},
title = {i-Motif DNA: structural features and significance to cell biology},
journal = {Nucleic Acids Research},
year = {2018},
volume = {46},
publisher = {Oxford University Press},
month = {aug},
url = {https://doi.org/10.1093/nar/gky735},
number = {16},
pages = {8038--8056},
doi = {10.1093/nar/gky735}
}
Cite this
MLA
Copy
Abou Assi, Hala, et al. “i-Motif DNA: structural features and significance to cell biology.” Nucleic Acids Research, vol. 46, no. 16, Aug. 2018, pp. 8038-8056. https://doi.org/10.1093/nar/gky735.