Plant Cell

, volume 36 , issue 11 , pages 4703-4715

Integration of biological and information technologies to enhance plant autoluminescence

Jieyu Ge ^{1, 2}

Xuye Lang ^{3, 4, 5, 6}

Jiayi Ji ^{1, 2}

Chengyi Qu ^{1, 2}

He Qiao ^{3, 4, 5, 6}

Jingling Zhong ^{1, 2}

Daren Luo ^{1, 2}

Jin Hu ^{1, 2}

Hongyu Chen ^{1, 2}

Shun Wang ^{1, 2}

Tiange Wang ^{1, 2}

Shiquan Li ^{1, 2}

Wei Li ^{1, 2, 3, 5}

Peng Zheng ^{1, 2, 3, 5}

Jiming Xu ^{7, 8}

Hao Du ^{1, 2, 3, 5}

Hide authors affiliations Show authors affiliations: 8 affiliations

College of Agriculture and Biotechnology, Zhejiang University , Hangzhou 310058 , China |

College of Agriculture and Biotechnology, Zhejiang University , Hangzhou 310058 , |

ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University , Hangzhou 311215 , China |

⁴

College of Chemical and Biological Engineering, Zhejiang University , Hangzhou 310058 , China |

⁵

ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University , Hangzhou 311215 , |

⁶

College of Chemical and Biological Engineering, Zhejiang University , Hangzhou 310058 , |

⁷

State Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University , Hangzhou, Zhejiang 310058 , China |

⁸

State Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University , Hangzhou, Zhejiang 310058 , |

Publication type: Journal Article

Publication date: 2024-08-21

Oxford University Press

Plant Cell

scimago Q1

wos Q1

SJR: 3.704

CiteScore: 15.7

Impact factor: 11.6

ISSN: 10404651, 1532298X

DOI: 10.1093/plcell/koae236

Copy DOI

PubMed ID: 39167833

Abstract

Autoluminescent plants have been genetically modified to express the fungal bioluminescence pathway (FBP). However, a bottleneck in precursor production has limited the brightness of these luminescent plants. Here, we demonstrate the effectiveness of utilizing a computational model to guide a multiplex five-gene-silencing strategy by an artificial microRNA array to enhance caffeic acid and hispidin levels in plants. By combining loss-of-function-directed metabolic flux with a tyrosine-derived caffeic acid pathway, we achieved substantially enhanced bioluminescence levels. We successfully generated eFBP2 plants that emit considerably brighter bioluminescence for naked-eye reading by integrating all validated DNA modules. Our analysis revealed that the luminous energy conversion efficiency of the eFBP2 plants is currently very low, suggesting that luminescence intensity can be improved in future iterations. These findings highlight the potential to enhance plant luminescence through the integration of biological and information technologies.

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GOST |

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GOST Copy

Ge J. et al. Integration of biological and information technologies to enhance plant autoluminescence // Plant Cell. 2024. Vol. 36. No. 11. pp. 4703-4715.

GOST all authors (up to 50) Copy

Ge J., Lang X., Ji J., Qu C., Qiao H., Zhong J., Luo D., Hu J., Chen H., Wang S., Wang T., Li S., Li W., Zheng P., Xu J., Du H. Integration of biological and information technologies to enhance plant autoluminescence // Plant Cell. 2024. Vol. 36. No. 11. pp. 4703-4715.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1093/plcell/koae236

UR - https://academic.oup.com/plcell/advance-article/doi/10.1093/plcell/koae236/7738352

TI - Integration of biological and information technologies to enhance plant autoluminescence

T2 - Plant Cell

AU - Ge, Jieyu

AU - Lang, Xuye

AU - Ji, Jiayi

AU - Qu, Chengyi

AU - Qiao, He

AU - Zhong, Jingling

AU - Luo, Daren

AU - Hu, Jin

AU - Chen, Hongyu

AU - Wang, Shun

AU - Wang, Tiange

AU - Li, Shiquan

AU - Li, Wei

AU - Zheng, Peng

AU - Xu, Jiming

AU - Du, Hao

PY - 2024

DA - 2024/08/21

PB - Oxford University Press

SP - 4703-4715

IS - 11

VL - 36

PMID - 39167833

SN - 1040-4651

SN - 1532-298X

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2024_Ge,

author = {Jieyu Ge and Xuye Lang and Jiayi Ji and Chengyi Qu and He Qiao and Jingling Zhong and Daren Luo and Jin Hu and Hongyu Chen and Shun Wang and Tiange Wang and Shiquan Li and Wei Li and Peng Zheng and Jiming Xu and Hao Du},

title = {Integration of biological and information technologies to enhance plant autoluminescence},

journal = {Plant Cell},

year = {2024},

volume = {36},

publisher = {Oxford University Press},

month = {aug},

url = {https://academic.oup.com/plcell/advance-article/doi/10.1093/plcell/koae236/7738352},

number = {11},

pages = {4703--4715},

doi = {10.1093/plcell/koae236}

}

MLA

Cite this

MLA Copy

Ge, Jieyu, et al. “Integration of biological and information technologies to enhance plant autoluminescence.” Plant Cell, vol. 36, no. 11, Aug. 2024, pp. 4703-4715. https://academic.oup.com/plcell/advance-article/doi/10.1093/plcell/koae236/7738352.

Publisher

Oxford University Press

Journal

Plant Cell

scimago Q1

wos Q1

SJR

3.704

CiteScore

15.7

Impact factor

11.6

ISSN

10404651 (Print)

1532298X (Electronic)