Open Access
An update on smart biocatalysts for industrial and biomedical applications
Publication type: Journal Article
Publication date: 2018-02-28
scimago Q1
wos Q1
SJR: 1.025
CiteScore: 7.2
Impact factor: 3.5
ISSN: 17425689, 17425662
PubMed ID:
29491182
Biochemistry
Biophysics
Biotechnology
Bioengineering
Biomaterials
Biomedical Engineering
Abstract
Recently, smart biocatalysts, where enzymes are conjugated to stimuli-responsive (smart) polymers, have gained significant attention. Based on the presence or absence of external stimuli, the polymer attached to the enzyme changes its conformation to protect the enzyme from the external environment and regulate the enzyme activity, thus acting as a molecular switch. Owing to this behaviour, smart biocatalysts can be separated easily from a reaction mixture and re-used several times. Several such smart polymer-based biocatalysts have been developed for industrial and biomedical applications. In addition, they have been used in biosensors, biometrics and nano-electronic devices. This review article covers recent advances in developing different kinds of stimuli-responsive enzyme bioconjugates, including conjugation strategies, and their applications.
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38
Total citations:
38
Citations from 2024:
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(13.15%)
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GOST
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Shakya A. K., Selva Nandakumar K. An update on smart biocatalysts for industrial and biomedical applications // Journal of the Royal Society Interface. 2018. Vol. 15. No. 139. p. 20180062.
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Shakya A. K., Selva Nandakumar K. An update on smart biocatalysts for industrial and biomedical applications // Journal of the Royal Society Interface. 2018. Vol. 15. No. 139. p. 20180062.
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RIS
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TY - JOUR
DO - 10.1098/rsif.2018.0062
UR - https://doi.org/10.1098/rsif.2018.0062
TI - An update on smart biocatalysts for industrial and biomedical applications
T2 - Journal of the Royal Society Interface
AU - Shakya, Akhilesh Kumar
AU - Selva Nandakumar, Kutty
PY - 2018
DA - 2018/02/28
PB - The Royal Society
SP - 20180062
IS - 139
VL - 15
PMID - 29491182
SN - 1742-5689
SN - 1742-5662
ER -
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BibTex (up to 50 authors)
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@article{2018_Shakya,
author = {Akhilesh Kumar Shakya and Kutty Selva Nandakumar},
title = {An update on smart biocatalysts for industrial and biomedical applications},
journal = {Journal of the Royal Society Interface},
year = {2018},
volume = {15},
publisher = {The Royal Society},
month = {feb},
url = {https://doi.org/10.1098/rsif.2018.0062},
number = {139},
pages = {20180062},
doi = {10.1098/rsif.2018.0062}
}
Cite this
MLA
Copy
Shakya, Akhilesh Kumar, et al. “An update on smart biocatalysts for industrial and biomedical applications.” Journal of the Royal Society Interface, vol. 15, no. 139, Feb. 2018, p. 20180062. https://doi.org/10.1098/rsif.2018.0062.