Open Access
,
volume 80
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issue 11
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pages 1221-1225
Synthesis, crystal structure and Hirshfeld surface analysis of 2-{4-[(2-chlorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl}-N-phenylacetamide
Publication type: Journal Article
Publication date: 2024-10-31
scimago Q4
wos Q4
SJR: 0.197
CiteScore: 1.2
Impact factor: 0.6
ISSN: 20569890
PubMed ID:
39712150
Abstract
In the title molecule, C20H18ClN3O2, the 2-chlorophenyl group is disordered to a small extent [occupancies 0.875 (2)/0.125 (2)]. The phenylacetamide moiety is nearly planar due to a weak, intramolecular C—H...O hydrogen bond. In the crystal, N—H...O hydrogen bonds and π-stacking interactions between pyridazine and phenyl rings form helical chains of molecules in the b-axis direction, which are linked by C—H...O hydrogen bonds and C—H...π(ring) interactions. A Hirshfeld surface analysis was performed, which showed that H...H, C...H/H...C and O...H/H...O interactions to dominate the intermolecular contacts in the crystal.
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Assila H. et al. Synthesis, crystal structure and Hirshfeld surface analysis of 2-{4-[(2-chlorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl}-N-phenylacetamide // Acta Crystallographica Section E: Crystallographic Communications. 2024. Vol. 80. No. 11. pp. 1221-1225.
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Assila H., Zaoui Y., Guerrab W., Ramli Y., Ansar M. Synthesis, crystal structure and Hirshfeld surface analysis of 2-{4-[(2-chlorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl}-N-phenylacetamide // Acta Crystallographica Section E: Crystallographic Communications. 2024. Vol. 80. No. 11. pp. 1221-1225.
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TY - JOUR
DO - 10.1107/s2056989024010296
UR - https://journals.iucr.org/paper?S2056989024010296
TI - Synthesis, crystal structure and Hirshfeld surface analysis of 2-{4-[(2-chlorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl}-N-phenylacetamide
T2 - Acta Crystallographica Section E: Crystallographic Communications
AU - Assila, Hamza
AU - Zaoui, Younes
AU - Guerrab, Walid
AU - Ramli, Youssef
AU - Ansar, M'hammed
PY - 2024
DA - 2024/10/31
PB - International Union of Crystallography (IUCr)
SP - 1221-1225
IS - 11
VL - 80
PMID - 39712150
SN - 2056-9890
ER -
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@article{2024_Assila,
author = {Hamza Assila and Younes Zaoui and Walid Guerrab and Youssef Ramli and M'hammed Ansar},
title = {Synthesis, crystal structure and Hirshfeld surface analysis of 2-{4-[(2-chlorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl}-N-phenylacetamide},
journal = {Acta Crystallographica Section E: Crystallographic Communications},
year = {2024},
volume = {80},
publisher = {International Union of Crystallography (IUCr)},
month = {oct},
url = {https://journals.iucr.org/paper?S2056989024010296},
number = {11},
pages = {1221--1225},
doi = {10.1107/s2056989024010296}
}
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Assila, Hamza, et al. “Synthesis, crystal structure and Hirshfeld surface analysis of 2-{4-[(2-chlorophenyl)methyl]-3-methyl-6-oxopyridazin-1-yl}-N-phenylacetamide.” Acta Crystallographica Section E: Crystallographic Communications, vol. 80, no. 11, Oct. 2024, pp. 1221-1225. https://journals.iucr.org/paper?S2056989024010296.
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