Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking
M N Yakovtseva
1
,
Oshra Betzer
2
,
A V Lunin
1
,
Elizaveta N Mochalova
3, 4
,
M Beiderman
2
,
M. Motiei
2
,
S. D. Zvereva
1
,
O B Proushinskaya
1
,
T Sadan
2
,
R Popovtzer
2
,
Publication type: Proceedings Article
Publication date: 2020-11-02
Abstract
To date, targeting cancer cells by nanoparticles has been limited due to physical and biological obstructions, including the mononuclear phagocyte system. A novel approach for prolongation of nanoparticle circulation is cellular ‘hitchhiking’, or use of cells as vehicles to increase co-delivery of cancer therapeutics and particles to affected tissue. In this work, we studied the main characteristics of nanoagents based on magnetic and gold particles, to ensure optimal physicochemical characteristics. The developed agents hold promise to overcome the challenges that still hinder effective drug delivery for treatment of such complex diseases as cancer.
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Yakovtseva M. N. et al. Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking // Proceedings - International Conference Laser Optics 2020, ICLO 2020. 2020.
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Yakovtseva M. N., Betzer O., Lunin A. V., Mochalova E. N., Beiderman M., Motiei M., Zvereva S. D., Proushinskaya O. B., Sadan T., Popovtzer R., Nikitin M. V. Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking // Proceedings - International Conference Laser Optics 2020, ICLO 2020. 2020.
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TY - CPAPER
DO - 10.1109/ICLO48556.2020.9285858
UR - https://doi.org/10.1109/ICLO48556.2020.9285858
TI - Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking
T2 - Proceedings - International Conference Laser Optics 2020, ICLO 2020
AU - Yakovtseva, M N
AU - Betzer, Oshra
AU - Lunin, A V
AU - Mochalova, Elizaveta N
AU - Beiderman, M
AU - Motiei, M.
AU - Zvereva, S. D.
AU - Proushinskaya, O B
AU - Sadan, T
AU - Popovtzer, R
AU - Nikitin, Maksim V
PY - 2020
DA - 2020/11/02
PB - Institute of Electrical and Electronics Engineers (IEEE)
ER -
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@inproceedings{2020_Yakovtseva,
author = {M N Yakovtseva and Oshra Betzer and A V Lunin and Elizaveta N Mochalova and M Beiderman and M. Motiei and S. D. Zvereva and O B Proushinskaya and T Sadan and R Popovtzer and Maksim V Nikitin},
title = {Magnetic and Gold Nanoparticles Optimized for Cancer Treatment via Cell Hitchhiking},
year = {2020},
month = {nov},
publisher = {Institute of Electrical and Electronics Engineers (IEEE)}
}