Immunoglobulin-based hybrid targeted nanoagents for in vitro and in vivo multimodal imaging

Nanomedicine constantly broadens horizons of modern therapy and diagnostics. However, imaging nanoagents are of especial interest. Here, we report on novel, facile, and sustainable way to fabricate targeted multimodal imaging nanoparticles. Specifically, we synthesize nanoparticles using immunoglobulins and introduce nanoparticles of different nature into immunoglobulin-based matrix. We demonstrate applicability of the nanoparticles both in vitro and in vivo.