IEEE Transactions on Medical Imaging, volume 40, issue 4, pages 1207-1216

Skin Complications of Diabetes Mellitus Revealed by Polarized Hyperspectral Imaging and Machine Learning

Dremin Viktor ^{1, 2}

Marcinkevics Zbignevs ³

Zherebtsov Evgeny ²

Popov Alexey ⁴

Grabovskis Andris ⁵

Kronberga Hedviga ⁶

Geldnere Kristine ⁷

Doronin Alexander ⁸

MEGLINSKI IGOR ^{1, 9, 10, 11}

Bykov Alexander ²

Hide authors affiliations Show authors affiliations: 11 affiliations

College of Engineering and Physical Sciences, Aston University, Birmingham, U.K |

Opto-Electronics and Measurement Techniques Unit, University of Oulu, Oulu, Finland |

Department of Human and Animal Physiology, University of Latvia, Riga, Latvia |

⁴

Vtt Technical Research Centre of Finland, Oulu, Finland |

⁵

Biophotonics Laboratory, Institute of Atomic Physics and Spectroscopy, University of Latvia, Riga, Latvia |

⁶

Medical Center Plavnieki, Riga, Latvia |

⁷

Pauls Stradins Clinical University Hospital, Riga, Latvia |

⁸

Computer Graphics Group, School of Engineering and Computer Science, Victoria University of Wellington, Wellington, New Zealand |

⁹

Institute of Engineering Physics for Biomedicine (PhysBio), National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Moscow, Russia |

¹⁰

Interdisciplinary Laboratory of Biophotonics, National Research Tomsk State University, Tomsk, Russia |

¹¹

Institute of Clinical Medicine N.V. Sklifosovsky, I.M. Sechenov First Moscow State Medical University, Moscow, Russia

Sechenov First Moscow State Medical University

Sclifosovsky Research Institute for Emergency Medicine

Publication type: Journal Article

Publication date: 2021-04-01

IEEE

Journal: IEEE Transactions on Medical Imaging

Quartile SCImago

Quartile WOS

Impact factor: 10.6

ISSN: 02780062, 15580062

DOI: 10.1109/TMI.2021.3049591

Copy DOI

Computer Science Applications

Electrical and Electronic Engineering

Radiological and Ultrasound Technology

Software

Abstract

Aging and diabetes lead to protein glycation and cause dysfunction of collagen-containing tissues. The accompanying structural and functional changes of collagen significantly contribute to the development of various pathological malformations affecting the skin, blood vessels, and nerves, causing a number of complications, increasing disability risks and threat to life. In fact, no methods of non-invasive assessment of glycation and associated metabolic processes in biotissues or prediction of possible skin complications, e.g., ulcers, currently exist for endocrinologists and clinical diagnosis. In this publication, utilizing emerging photonics-based technology, innovative solutions in machine learning, and definitive physiological characteristics, we introduce a diagnostic approach capable of evaluating the skin complications of diabetes mellitus at the very earlier stage. The results of the feasibility studies, as well as the actual tests on patients with diabetes and healthy volunteers, clearly show the ability of the approach to differentiate diabetic and control groups. Furthermore, the developed in-house polarization-based hyperspectral imaging technique accomplished with the implementation of the artificial neural network provides new horizons in the study and diagnosis of age-related diseases.

By date By citations

Citations by journals

	1 2 3 4 5 6
Biomedical Optics Express	Biomedical Optics Express, 6, 11.32% Biomedical Optics Express 6 publications, 11.32%
Journal of Biomedical Optics	Journal of Biomedical Optics, 3, 5.66% Journal of Biomedical Optics 3 publications, 5.66%
Applied Sciences (Switzerland)	Applied Sciences (Switzerland), 2, 3.77% Applied Sciences (Switzerland) 2 publications, 3.77%
Sensors	Sensors, 2, 3.77% Sensors 2 publications, 3.77%
Scientific Reports	Scientific Reports, 2, 3.77% Scientific Reports 2 publications, 3.77%
Signal Processing	Signal Processing, 2, 3.77% Signal Processing 2 publications, 3.77%
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing	IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2, 3.77% IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing 2 publications, 3.77%
Frontiers in Physics	Frontiers in Physics, 1, 1.89% Frontiers in Physics 1 publication, 1.89%
Translational Biophotonics: Diagnostics and Therapeutics	Translational Biophotonics: Diagnostics and Therapeutics, 1, 1.89% Translational Biophotonics: Diagnostics and Therapeutics 1 publication, 1.89%
IEEE Transactions on Geoscience and Remote Sensing	IEEE Transactions on Geoscience and Remote Sensing, 1, 1.89% IEEE Transactions on Geoscience and Remote Sensing 1 publication, 1.89%
Biomedizinische Technik	Biomedizinische Technik, 1, 1.89% Biomedizinische Technik 1 publication, 1.89%
Frontiers in Endocrinology	Frontiers in Endocrinology, 1, 1.89% Frontiers in Endocrinology 1 publication, 1.89%
Biosensors	Biosensors, 1, 1.89% Biosensors 1 publication, 1.89%
Artificial Life and Robotics	Artificial Life and Robotics, 1, 1.89% Artificial Life and Robotics 1 publication, 1.89%
Communications Biology	Communications Biology, 1, 1.89% Communications Biology 1 publication, 1.89%
International Journal of Optomechatronics	International Journal of Optomechatronics, 1, 1.89% International Journal of Optomechatronics 1 publication, 1.89%
Optics and Lasers in Engineering	Optics and Lasers in Engineering, 1, 1.89% Optics and Lasers in Engineering 1 publication, 1.89%
Applied Intelligence	Applied Intelligence, 1, 1.89% Applied Intelligence 1 publication, 1.89%
Expert Systems	Expert Systems, 1, 1.89% Expert Systems 1 publication, 1.89%
SN Computer Science	SN Computer Science, 1, 1.89% SN Computer Science 1 publication, 1.89%
Journal of Healthcare Engineering	Journal of Healthcare Engineering, 1, 1.89% Journal of Healthcare Engineering 1 publication, 1.89%
Scientific data	Scientific data, 1, 1.89% Scientific data 1 publication, 1.89%
Lecture Notes in Computer Science	Lecture Notes in Computer Science, 1, 1.89% Lecture Notes in Computer Science 1 publication, 1.89%
Soft Computing	Soft Computing, 1, 1.89% Soft Computing 1 publication, 1.89%
IEEE Transactions on Network and Service Management	IEEE Transactions on Network and Service Management, 1, 1.89% IEEE Transactions on Network and Service Management 1 publication, 1.89%
Photonics	Photonics, 1, 1.89% Photonics 1 publication, 1.89%
Agriculture (Switzerland)	Agriculture (Switzerland), 1, 1.89% Agriculture (Switzerland) 1 publication, 1.89%
Expert Systems with Applications	Expert Systems with Applications, 1, 1.89% Expert Systems with Applications 1 publication, 1.89%
Optics Express	Optics Express, 1, 1.89% Optics Express 1 publication, 1.89%
	1 2 3 4 5 6

Citations by publishers

	1 2 3 4 5 6 7 8 9
Springer Nature	Springer Nature, 9, 16.98% Springer Nature 9 publications, 16.98%
Optical Society of America	Optical Society of America, 7, 13.21% Optical Society of America 7 publications, 13.21%
Multidisciplinary Digital Publishing Institute (MDPI)	Multidisciplinary Digital Publishing Institute (MDPI), 7, 13.21% Multidisciplinary Digital Publishing Institute (MDPI) 7 publications, 13.21%
IEEE	IEEE, 6, 11.32% IEEE 6 publications, 11.32%
Elsevier	Elsevier, 5, 9.43% Elsevier 5 publications, 9.43%
SPIE	SPIE, 4, 7.55% SPIE 4 publications, 7.55%
Frontiers Media S.A.	Frontiers Media S.A., 2, 3.77% Frontiers Media S.A. 2 publications, 3.77%
Walter de Gruyter	Walter de Gruyter, 1, 1.89% Walter de Gruyter 1 publication, 1.89%
Taylor & Francis	Taylor & Francis, 1, 1.89% Taylor & Francis 1 publication, 1.89%
Wiley	Wiley, 1, 1.89% Wiley 1 publication, 1.89%
Hindawi Limited	Hindawi Limited, 1, 1.89% Hindawi Limited 1 publication, 1.89%
Korean Academy of Medical Sciences	Korean Academy of Medical Sciences, 1, 1.89% Korean Academy of Medical Sciences 1 publication, 1.89%
	1 2 3 4 5 6 7 8 9

We do not take into account publications that without a DOI.
Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
Statistics recalculated weekly.

{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2021,2022,2023,2024],"ids":[0,0,0,0],"codes":[0,0,0,0],"imageUrls":["","","",""],"datasets":[{"label":"Citations number","data":[8,13,28,4],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["15.09","24.53","52.83","7.55"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Biomedical Optics Express","Journal of Biomedical Optics","Applied Sciences (Switzerland)","Sensors","Scientific Reports","Signal Processing","IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing","Frontiers in Physics","Translational Biophotonics: Diagnostics and Therapeutics","IEEE Transactions on Geoscience and Remote Sensing","Biomedizinische Technik","Frontiers in Endocrinology","Biosensors","Artificial Life and Robotics","Communications Biology","International Journal of Optomechatronics","Optics and Lasers in Engineering","Applied Intelligence","Expert Systems","SN Computer Science","Journal of Healthcare Engineering","Scientific data","Lecture Notes in Computer Science","Soft Computing","IEEE Transactions on Network and Service Management","Photonics","Agriculture (Switzerland)","Expert Systems with Applications","Optics Express"],"ids":[14292,11544,16650,18435,13767,11830,9243,9538,57088,12644,11329,19896,5233,916,11778,20771,20308,13029,10456,28878,8249,2082,1022,19349,7986,12741,3500,7342,8923],"codes":[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/bypZPcr6C4twKiQVCUCGc0GF4cH6aUWmpClD3hsH_medium.webp","\/storage\/images\/resized\/DBpVkewJngs3BK2gVqHayOcCZf2Czbxddw6ObU26_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/6scCJegesojp2jubwY3uKCzTAmgsaH2GIFlg6Hfk_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/DBpVkewJngs3BK2gVqHayOcCZf2Czbxddw6ObU26_medium.webp","\/storage\/images\/resized\/6scCJegesojp2jubwY3uKCzTAmgsaH2GIFlg6Hfk_medium.webp","\/storage\/images\/resized\/3SpVxcYL33bOvPq4sHxJLH2NeKNeDloahSUpNiO4_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/6scCJegesojp2jubwY3uKCzTAmgsaH2GIFlg6Hfk_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bypZPcr6C4twKiQVCUCGc0GF4cH6aUWmpClD3hsH_medium.webp"],"datasets":[{"label":"","data":[6,3,2,2,2,2,2,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[11.32,5.66,3.77,3.77,3.77,3.77,3.77,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89,1.89],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Springer Nature","Optical Society of America","Multidisciplinary Digital Publishing Institute (MDPI)","IEEE","Elsevier","SPIE","Frontiers Media S.A.","Walter de Gruyter","Taylor & Francis","Wiley","Hindawi Limited","Korean Academy of Medical Sciences"],"ids":[8,375,202,6953,17,7162,208,4,18,11,6921,6289],"codes":[0,0,0,0,0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/voXLqlsvTwv5p3iMQ8Dhs95nqB4AXOG7Taj7G4ra_medium.webp","\/storage\/images\/resized\/bypZPcr6C4twKiQVCUCGc0GF4cH6aUWmpClD3hsH_medium.webp","\/storage\/images\/resized\/MjH1ITP7lMYGxeqUZfkt2BnVLgjkk413jwBV97XX_medium.webp","\/storage\/images\/resized\/6scCJegesojp2jubwY3uKCzTAmgsaH2GIFlg6Hfk_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/DBpVkewJngs3BK2gVqHayOcCZf2Czbxddw6ObU26_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/3SpVxcYL33bOvPq4sHxJLH2NeKNeDloahSUpNiO4_medium.webp","\/storage\/images\/resized\/5YZtvLvkPZuc2JHOaZsjCvGSHFCuC3drUwN3YAc5_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/hqfzhQAjTGlNSRs6yzFNITgjSMm9Jr2QuotJHIvE_medium.webp",""],"datasets":[{"label":"","data":[9,7,7,6,5,4,2,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[16.98,13.21,13.21,11.32,9.43,7.55,3.77,1.89,1.89,1.89,1.89,1.89],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"}},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"}}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}

Metrics

Cite this

GOST |

Cite this

GOST Copy

Dremin V. et al. Skin Complications of Diabetes Mellitus Revealed by Polarized Hyperspectral Imaging and Machine Learning // IEEE Transactions on Medical Imaging. 2021. Vol. 40. No. 4. pp. 1207-1216.

GOST all authors (up to 50) Copy

Dremin V., Marcinkevics Z., Zherebtsov E., Popov A., Grabovskis A., Kronberga H., Geldnere K., Doronin A., MEGLINSKI I., Bykov A. Skin Complications of Diabetes Mellitus Revealed by Polarized Hyperspectral Imaging and Machine Learning // IEEE Transactions on Medical Imaging. 2021. Vol. 40. No. 4. pp. 1207-1216.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1109/TMI.2021.3049591

UR - https://doi.org/10.1109%2FTMI.2021.3049591

TI - Skin Complications of Diabetes Mellitus Revealed by Polarized Hyperspectral Imaging and Machine Learning

T2 - IEEE Transactions on Medical Imaging

AU - Dremin, Viktor

AU - Marcinkevics, Zbignevs

AU - Zherebtsov, Evgeny

AU - Popov, Alexey

AU - Grabovskis, Andris

AU - Kronberga, Hedviga

AU - Geldnere, Kristine

AU - Doronin, Alexander

AU - MEGLINSKI, IGOR

AU - Bykov, Alexander

PY - 2021

DA - 2021/04/01 00:00:00

PB - IEEE

SP - 1207-1216

IS - 4

VL - 40

SN - 0278-0062

SN - 1558-0062

ER -

BibTex |

Cite this

BibTex Copy

@article{2021_Dremin,

author = {Viktor Dremin and Zbignevs Marcinkevics and Evgeny Zherebtsov and Alexey Popov and Andris Grabovskis and Hedviga Kronberga and Kristine Geldnere and Alexander Doronin and IGOR MEGLINSKI and Alexander Bykov},

title = {Skin Complications of Diabetes Mellitus Revealed by Polarized Hyperspectral Imaging and Machine Learning},

journal = {IEEE Transactions on Medical Imaging},

year = {2021},

volume = {40},

publisher = {IEEE},

month = {apr},

url = {https://doi.org/10.1109%2FTMI.2021.3049591},

number = {4},

pages = {1207--1216},

doi = {10.1109/TMI.2021.3049591}

}

MLA

Cite this

MLA Copy

Dremin, Viktor, et al. “Skin Complications of Diabetes Mellitus Revealed by Polarized Hyperspectral Imaging and Machine Learning.” IEEE Transactions on Medical Imaging, vol. 40, no. 4, Apr. 2021, pp. 1207-1216. https://doi.org/10.1109%2FTMI.2021.3049591.

Found error?

Publisher

IEEE

Journal

IEEE Transactions on Medical Imaging

Quartile SCImago

Quartile WOS

Impact factor

10.6

ISSN

02780062 (Print)
15580062 (Electronic)

Profiles