Journal of Medical Imaging and Radiation Oncology, volume 62, issue 2, pages 232-239
Moderate hypofractionation for prostate cancer: A user's guide
David Pryor
1, 2
,
Sandra Turner
3, 4
,
Keen-Hun Tai
5, 6
,
Colin Tang
7
,
Giuseppe Sasso
8, 9
,
Marcus Dreosti
10
,
Henry H. Woo
11
,
Lee Wilton
12
,
Jarad M. Martin
12, 13
10
Genesis Cancer Care; Adelaide South Australia Australia
|
11
12
Calvary Mater Newcastle; Waratah New South Wales Australia
|
Publication type: Journal Article
Publication date: 2018-01-16
Quartile SCImago
Q3
Quartile WOS
Q4
Impact factor: 1.6
ISSN: 17549477, 17549485
Oncology
Radiology, Nuclear Medicine and imaging
Abstract
Three large randomised controlled trials have been published in the last year demonstrating the non-inferiority of moderate hypofractionation compared to conventional fractionation for localised prostate cancer with respect to both disease control and late toxicity at 5 years. Furthermore, no clinically significant differences in patient-reported outcomes have emerged. More mature follow-up data are now also available from phase 2 studies confirming that moderate hypofractionation is associated with low rates of significant toxicity at 10 years. Moving forward it is likely that appropriate patient selection, integration of androgen deprivation and attention to optimising technique will play a more important role than modest differences in dose-fractionation schedules. Here we briefly review the evidence, discuss issues of patient selection and provide an approach to implementing moderately hypofractionated radiation therapy for prostate cancer in clinical practice.
Top-30
Citations by journals
|
1
2
|
|
|
Journal of Medical Imaging and Radiation Oncology
2 publications, 22.22%
|
|
|
Frontiers in Oncology
1 publication, 11.11%
|
|
|
Clinical and Translational Radiation Oncology
1 publication, 11.11%
|
|
|
Practical Radiation Oncology
1 publication, 11.11%
|
|
|
International Journal of Radiation Oncology Biology Physics
1 publication, 11.11%
|
|
|
Medical Physics
1 publication, 11.11%
|
|
|
BMJ Open
1 publication, 11.11%
|
|
|
Advances in Radiation Oncology
1 publication, 11.11%
|
|
|
1
2
|
Citations by publishers
|
1
2
3
4
|
|
|
Elsevier
4 publications, 44.44%
|
|
|
Wiley
3 publications, 33.33%
|
|
|
Frontiers Media S.A.
1 publication, 11.11%
|
|
|
BMJ
1 publication, 11.11%
|
|
|
1
2
3
4
|
- We do not take into account publications without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
{"yearsCitations":{"type":"bar","data":{"show":true,"labels":[2019,2020,2021,2022,2023,2024],"ids":[0,0,0,0,0,0],"codes":[0,0,0,0,0,0],"imageUrls":["","","","","",""],"datasets":[{"label":"Citations number","data":[2,2,3,1,0,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":["22.22","22.22","33.33","11.11",0,"11.11"],"barThickness":null}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"journals":{"type":"bar","data":{"show":true,"labels":["Journal of Medical Imaging and Radiation Oncology","Frontiers in Oncology","Clinical and Translational Radiation Oncology","Practical Radiation Oncology","International Journal of Radiation Oncology Biology Physics","Medical Physics","BMJ Open","Advances in Radiation Oncology"],"ids":[16992,10990,19801,15030,14734,2518,5113,2340],"codes":[0,0,0,0,0,0,0,0],"imageUrls":["\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/hysFKdIDQMKHPbF1uLxJ3M6dQA4gPVuC6ZeA7m5a_medium.webp","\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp"],"datasets":[{"label":"","data":[2,1,1,1,1,1,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[22.22,11.11,11.11,11.11,11.11,11.11,11.11,11.11],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Journals","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"publishers":{"type":"bar","data":{"show":true,"labels":["Elsevier","Wiley","Frontiers Media S.A.","BMJ"],"ids":[17,11,208,6954],"codes":[0,0,0,0],"imageUrls":["\/storage\/images\/resized\/GDnYOu1UpMMfMMRV6Aqle4H0YLLsraeD9IP9qScG_medium.webp","\/storage\/images\/resized\/bRyGpdm98BkAUYiK1YFNpl5Z7hPu6Gd87gbIeuG3_medium.webp","\/storage\/images\/resized\/4QWA67eqfcfyOiA8Wk7YnqroHFqQbTsmDJUYTCTg_medium.webp","\/storage\/images\/resized\/hysFKdIDQMKHPbF1uLxJ3M6dQA4gPVuC6ZeA7m5a_medium.webp"],"datasets":[{"label":"","data":[4,3,1,1],"backgroundColor":["#3B82F6","#3B82F6","#3B82F6","#3B82F6"],"percentage":[44.44,33.33,11.11,11.11],"barThickness":13}]},"options":{"indexAxis":"y","maintainAspectRatio":false,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false},"x":{"ticks":{"stepSize":null,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":false}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Publishers","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartiles":{"type":"bar","data":{"show":true,"labels":[2019,2020,2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[0,0,0,0,0,0],"percentage":["0","0","0","0","0","0"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[0,0,1,1,0,0],"percentage":["0","0","11.11","11.11","0","0"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[1,0,0,0,0,1],"percentage":["11.11","0","0","0","0","11.11"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[1,2,2,0,0,0],"percentage":["11.11","22.22","22.22","0","0","0"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,0,0,0,0,0],"percentage":["0","0","0","0","0","0"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by SCImago per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}},"yearsCitationsQuartilesWs":{"type":"bar","data":{"show":true,"labels":[2019,2020,2021,2022,2023,2024],"ids":[],"codes":[],"imageUrls":[],"datasets":[{"label":"Q4","backgroundColor":"rgb(221,90,78)","data":[0,0,1,1,0,0],"percentage":["0","0","11.11","11.11","0","0"]},{"label":"Q3","backgroundColor":"rgb(251, 163,83)","data":[0,0,0,0,0,0],"percentage":["0","0","0","0","0","0"]},{"label":"Q2","backgroundColor":"rgb(232, 213, 89)","data":[2,2,1,0,0,0],"percentage":["22.22","22.22","11.11","0","0","0"]},{"label":"Q1","backgroundColor":"rgb(164, 207, 99)","data":[0,0,1,0,0,0],"percentage":["0","0","11.11","0","0","0"]},{"label":"Quartile not defined","backgroundColor":"#E5E7EB","data":[0,0,0,0,0,1],"percentage":["0","0","0","0","0","11.11"]}]},"options":{"indexAxis":"x","maintainAspectRatio":true,"scales":{"y":{"ticks":{"precision":0,"autoSkip":false,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true},"x":{"ticks":{"stepSize":1,"precision":0,"font":{"family":"Montserrat"},"color":"#000000"},"stacked":true}},"plugins":{"legend":{"position":"top","labels":{"font":{"family":"Montserrat"},"color":"#000000"}},"title":{"display":true,"text":"Citations quartiles by WoS per year","font":{"size":24,"family":"Montserrat","weight":600},"color":"#000000"}}}}}
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
Cite this
GOST |
RIS |
BibTex |
MLA
Cite this
GOST
Copy
Pryor D. et al. Moderate hypofractionation for prostate cancer: A user's guide // Journal of Medical Imaging and Radiation Oncology. 2018. Vol. 62. No. 2. pp. 232-239.
GOST all authors (up to 50)
Copy
Pryor D., Turner S., Tai K., Tang C., Sasso G., Dreosti M., Woo H. H., Wilton L., Martin J. M. Moderate hypofractionation for prostate cancer: A user's guide // Journal of Medical Imaging and Radiation Oncology. 2018. Vol. 62. No. 2. pp. 232-239.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1111/1754-9485.12703
UR - https://doi.org/10.1111/1754-9485.12703
TI - Moderate hypofractionation for prostate cancer: A user's guide
T2 - Journal of Medical Imaging and Radiation Oncology
AU - Tang, Colin
AU - Sasso, Giuseppe
AU - Dreosti, Marcus
AU - Pryor, David
AU - Wilton, Lee
AU - Turner, Sandra
AU - Tai, Keen-Hun
AU - Woo, Henry H.
AU - Martin, Jarad M.
PY - 2018
DA - 2018/01/16 00:00:00
PB - Wiley
SP - 232-239
IS - 2
VL - 62
SN - 1754-9477
SN - 1754-9485
ER -
Cite this
BibTex
Copy
@article{2018_Pryor,
author = {Colin Tang and Giuseppe Sasso and Marcus Dreosti and David Pryor and Lee Wilton and Sandra Turner and Keen-Hun Tai and Henry H. Woo and Jarad M. Martin},
title = {Moderate hypofractionation for prostate cancer: A user's guide},
journal = {Journal of Medical Imaging and Radiation Oncology},
year = {2018},
volume = {62},
publisher = {Wiley},
month = {jan},
url = {https://doi.org/10.1111/1754-9485.12703},
number = {2},
pages = {232--239},
doi = {10.1111/1754-9485.12703}
}
Cite this
MLA
Copy
Pryor, David, et al. “Moderate hypofractionation for prostate cancer: A user's guide.” Journal of Medical Imaging and Radiation Oncology, vol. 62, no. 2, Jan. 2018, pp. 232-239. https://doi.org/10.1111/1754-9485.12703.