volume 59 issue 5 pages 632-644

Review article: Advances in the management of lower gastrointestinal bleeding

Ali Alali 1
Majid A Almadi 2, 3
Publication typeJournal Article
Publication date2023-12-29
scimago Q1
wos Q1
SJR2.892
CiteScore13.0
Impact factor6.7
ISSN02692813, 13652036
PubMed ID:  38158721
Pharmacology (medical)
Gastroenterology
Hepatology
Abstract
Summary
Background

Lower gastrointestinal bleeding (LGIB) is a common emergency with substantial associated morbidity and mortality. Elective colonoscopy plays an essential role in management, with an even more important role for radiology in the acute setting. Recent advances in the management of patients with LGIB warrant review as the management has recently evolved.

Aims

To provide a comprehensive and updated overview of advances in the approach to patients with LGIB

Methods

We performed a comprehensive literature search to examine the current data for this narrative review supplemented by expert opinion.

Results

The incidence of LGIB is increasing worldwide, partly related to an ageing population and the increasing use of antithrombotics. Diverticulosis continues to be the most common aetiology of LGIB. Pre‐endoscopic risk stratification tools, especially the Oakland score, can aid appropriate patient triage. Adequate resuscitation continues to form the basis of management, while appropriate management of antithrombotics is crucial to balance the risk of worsening bleeding against increased cardiovascular risk. Radiological imaging plays an essential role in the diagnosis and treatment of acute LGIB, especially among unstable patients. Colonoscopy remains the gold‐standard test for the elective management of stable patients.

Conclusions

The management of LGIB has evolved significantly in recent years, with a shift towards radiological interventions for unstable patients while reserving elective colonoscopy for stable patients. A multidisciplinary approach is essential to optimise the outcomes of patients with LGIB.

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GOST |
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GOST Copy
Alali A. et al. Review article: Advances in the management of lower gastrointestinal bleeding // Alimentary Pharmacology and Therapeutics. 2023. Vol. 59. No. 5. pp. 632-644.
GOST all authors (up to 50) Copy
Alali A., Almadi M. A., Barkun A. N. Review article: Advances in the management of lower gastrointestinal bleeding // Alimentary Pharmacology and Therapeutics. 2023. Vol. 59. No. 5. pp. 632-644.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1111/apt.17859
UR - https://doi.org/10.1111/apt.17859
TI - Review article: Advances in the management of lower gastrointestinal bleeding
T2 - Alimentary Pharmacology and Therapeutics
AU - Alali, Ali
AU - Almadi, Majid A
AU - Barkun, Alan N.
PY - 2023
DA - 2023/12/29
PB - Wiley
SP - 632-644
IS - 5
VL - 59
PMID - 38158721
SN - 0269-2813
SN - 1365-2036
ER -
BibTex |
Cite this
BibTex (up to 50 authors) Copy
@article{2023_Alali,
author = {Ali Alali and Majid A Almadi and Alan N. Barkun},
title = {Review article: Advances in the management of lower gastrointestinal bleeding},
journal = {Alimentary Pharmacology and Therapeutics},
year = {2023},
volume = {59},
publisher = {Wiley},
month = {dec},
url = {https://doi.org/10.1111/apt.17859},
number = {5},
pages = {632--644},
doi = {10.1111/apt.17859}
}
MLA
Cite this
MLA Copy
Alali, Ali, et al. “Review article: Advances in the management of lower gastrointestinal bleeding.” Alimentary Pharmacology and Therapeutics, vol. 59, no. 5, Dec. 2023, pp. 632-644. https://doi.org/10.1111/apt.17859.
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