Worldwide expert recommendations for the diagnosis and management of vitiligo: Position statement from the international Vitiligo Task Force—Part 2: Specific treatment recommendations
Background
The treatment of vitiligo can be challenging. Up‐to‐date agreed consensus recommendations on the use of topical and systemic therapies to facilitate the clinical management of vitiligo are currently lacking.
Objectives
To develop internationally agreed‐upon expert‐based recommendations for the treatment of vitiligo.
Methods
In this consensus statement, a consortium of 42 international vitiligo experts and four patient representatives participated in different online and live meetings to develop a consensus management strategy for vitiligo. At least two vitiligo experts summarized the evidence for different topics included in the algorithms. A survey was then given to a core group of eight experts to resolve the remaining issues. Subsequently, the recommendations were finalized and validated based on further input from the entire group during two live meetings.
Results
The recommendations provided summarize the latest evidence regarding the use of topical therapies (steroids, calcineurin inhibitors and Jak‐inhibitors) and systemic therapies, including steroids and other systemic immunomodulating or antioxidant agents. The different modalities of phototherapies (NB‐UVB, photochemotherapy, excimer devices and home phototherapy), which are often combined with other therapies, are also summarized. Interventional approaches as well as depigmentation strategies are presented for specific indications. Finally, the status of innovative and targeted therapies under development is discussed.
Conclusions
This international consensus statement culminated in expert‐based clinical practice recommendations for the treatment of vitiligo. The development of new therapies is ongoing in vitiligo, and this will likely improve the future management of vitiligo, a disease that still has many unmet needs.
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Journal of the European Academy of Dermatology and Venereology
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Journal of the American Academy of Dermatology
6 публикаций, 4.69%
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Dermatology and Therapy
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Journal of Dermatological Treatment
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Frontiers in Immunology
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Clinical, Cosmetic and Investigational Dermatology
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JDDG - Journal of the German Society of Dermatology
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Photodermatology Photoimmunology and Photomedicine
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Journal of Cutaneous Medicine and Surgery
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Archives of Dermatological Research
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Dermato
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Journal of Investigative Dermatology
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Journal of Dermatology
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Dermatology
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Russian Journal of Skin and Venereal Diseases
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Annales de Dermatologie et de Venereologie
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Actas Dermo-Sifiliograficas
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Die Dermatologie
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Journal of Cosmetic Dermatology
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JEADV Clinical Practice
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British Journal of Dermatology
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JAMA Dermatology
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Clinical Reviews in Allergy and Immunology
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International Journal of Molecular Sciences
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Drugs
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Trends in Molecular Medicine
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EClinicalMedicine
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Wiley
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Elsevier
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Springer Nature
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Taylor & Francis
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MDPI
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Frontiers Media S.A.
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Eco-Vector LLC
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Ovid Technologies (Wolters Kluwer Health)
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JMIR Publications
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American Medical Association (AMA)
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Alfmed LLC
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XMLink
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Georg Thieme Verlag KG
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Edizioni Minerva Medica
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American Chemical Society (ACS)
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Hans Publishers
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Mary Ann Liebert
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American Society for Clinical Investigation
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