Alimentary Pharmacology and Therapeutics, volume 23, issue 7, pages 841-855

Systematic review: the use of mesalazine in inflammatory bowel disease

R Bergman 1
M Parkes 1
1
 
Department of Gastroenterology, Addenbrooke's Hospital, Cambridge, UK.
Publication typeJournal Article
Publication date2006-04-01
Quartile SCImago
Q1
Quartile WOS
Q1
Impact factor7.6
ISSN02692813, 13652036
Pharmacology (medical)
Gastroenterology
Hepatology
Abstract
Mesalazine is among the medications most commonly prescribed by gastroenterologists, having to a large extent superseded sulfasalazine (sulphasalazine). However, there are still a number of aspects regarding its use which provoke debate and controversy.To provide a systematic assessment of the evidence for the use of mesalazine in ulcerative colitis and Crohn's disease.References were identified using PubMed database. Additional references were identified with related article searches.Mesalazine has a clear role in the maintenance of remission in ulcerative colitis and management of mild to moderately active disease, although the efficacy of topical preparations or combined topical and oral is clearly superior to oral alone. Evidence that increasing the dose of oral mesalazine improves efficacy is not clear-cut. The benefits of mesalazine in the management of acute Crohn's disease and the maintenance of remission are questionable and alternative treatments are usually more appropriate. Emerging evidence suggests that maintenance mesalazine reduces the risk of neoplastic progression in chronic ulcerative colitis. Compliance with therapy is thus important, as is an understanding of individuals most likely to default on this.Evidence for a beneficial effect of mesalazine is largely confined to the management of ulcerative colitis.

Top-30

Citations by journals

1
2
3
4
5
6
Journal of Molecular Liquids
6 publications, 6.45%
Gastroenterologia y Hepatologia
5 publications, 5.38%
Alimentary Pharmacology and Therapeutics
4 publications, 4.3%
Inflammatory Bowel Diseases
3 publications, 3.23%
Digestive Diseases
2 publications, 2.15%
World Journal of Gastroenterology
2 publications, 2.15%
Digestive Diseases and Sciences
2 publications, 2.15%
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
2 publications, 2.15%
Expert Opinion on Pharmacotherapy
2 publications, 2.15%
Pharmacogenomics
1 publication, 1.08%
Immunotherapy
1 publication, 1.08%
Orvosi Hetilap
1 publication, 1.08%
Breastfeeding Medicine
1 publication, 1.08%
Chemical and Pharmaceutical Bulletin
1 publication, 1.08%
Yakugaku Zasshi
1 publication, 1.08%
Journal of Clinical Gastroenterology
1 publication, 1.08%
European Journal of Gastroenterology and Hepatology
1 publication, 1.08%
Nihon Naika Gakkai Zasshi
1 publication, 1.08%
International Journal of Toxicology
1 publication, 1.08%
Journal of Clinical Medicine
1 publication, 1.08%
International Journal of Molecular Sciences
1 publication, 1.08%
BioMetals
1 publication, 1.08%
Gastroenterologe
1 publication, 1.08%
Journal of Medical Case Reports
1 publication, 1.08%
Clinical Pharmacokinetics
1 publication, 1.08%
Surgical Clinics of North America
1 publication, 1.08%
Primary Care - Clinics in Office Practice
1 publication, 1.08%
International Journal of Pharmaceutics
1 publication, 1.08%
Gastroenterology
1 publication, 1.08%
1
2
3
4
5
6

Citations by publishers

5
10
15
20
25
Elsevier
23 publications, 24.73%
Wiley
12 publications, 12.9%
Springer Nature
6 publications, 6.45%
Taylor & Francis
6 publications, 6.45%
Oxford University Press
5 publications, 5.38%
Multidisciplinary Digital Publishing Institute (MDPI)
3 publications, 3.23%
Future Medicine
2 publications, 2.15%
S. Karger AG
2 publications, 2.15%
Pharmaceutical Society of Japan
2 publications, 2.15%
Wolters Kluwer Health
2 publications, 2.15%
Baishideng Publishing Group
2 publications, 2.15%
Korean Society of Gastroenterology
2 publications, 2.15%
BMJ
2 publications, 2.15%
Akademiai Kiado
1 publication, 1.08%
Mary Ann Liebert
1 publication, 1.08%
Japanese Society of Internal Medicine
1 publication, 1.08%
SAGE
1 publication, 1.08%
Obsidiana Editores
1 publication, 1.08%
Pleiades Publishing
1 publication, 1.08%
Korean Association for the Study of Intestinal Diseases
1 publication, 1.08%
Royal College of Physicians
1 publication, 1.08%
Hindawi Limited
1 publication, 1.08%
American Association for Cancer Research (AACR)
1 publication, 1.08%
RCN Publishing
1 publication, 1.08%
Thieme
1 publication, 1.08%
Autonomous Non-profit Organization Editorial Board of the journal Uspekhi Khimii
1 publication, 1.08%
5
10
15
20
25
  • We do not take into account publications without a DOI.
  • Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
  • Statistics recalculated weekly.

Are you a researcher?

Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
Share
Cite this
GOST |
Cite this
GOST Copy
Bergman R., Parkes M. Systematic review: the use of mesalazine in inflammatory bowel disease // Alimentary Pharmacology and Therapeutics. 2006. Vol. 23. No. 7. pp. 841-855.
GOST all authors (up to 50) Copy
Bergman R., Parkes M. Systematic review: the use of mesalazine in inflammatory bowel disease // Alimentary Pharmacology and Therapeutics. 2006. Vol. 23. No. 7. pp. 841-855.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1111/j.1365-2036.2006.02846.x
UR - https://doi.org/10.1111/j.1365-2036.2006.02846.x
TI - Systematic review: the use of mesalazine in inflammatory bowel disease
T2 - Alimentary Pharmacology and Therapeutics
AU - Bergman, R
AU - Parkes, M
PY - 2006
DA - 2006/04/01 00:00:00
PB - Wiley
SP - 841-855
IS - 7
VL - 23
SN - 0269-2813
SN - 1365-2036
ER -
BibTex |
Cite this
BibTex Copy
@article{2006_Bergman,
author = {R Bergman and M Parkes},
title = {Systematic review: the use of mesalazine in inflammatory bowel disease},
journal = {Alimentary Pharmacology and Therapeutics},
year = {2006},
volume = {23},
publisher = {Wiley},
month = {apr},
url = {https://doi.org/10.1111/j.1365-2036.2006.02846.x},
number = {7},
pages = {841--855},
doi = {10.1111/j.1365-2036.2006.02846.x}
}
MLA
Cite this
MLA Copy
Bergman, R., and M Parkes. “Systematic review: the use of mesalazine in inflammatory bowel disease.” Alimentary Pharmacology and Therapeutics, vol. 23, no. 7, Apr. 2006, pp. 841-855. https://doi.org/10.1111/j.1365-2036.2006.02846.x.
Found error?