Open Access
Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 9917
The development of attenuation compensation models of fluorescence spectroscopy signals
1
State Univ. Education-Science-Production Complex (Russian Federation)
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Publication type: Proceedings Article
Publication date: 2016-04-21
Quartile SCImago
— Quartile WOS
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Impact factor: —
ISSN: 16057422
Abstract
This study examines the effect of blood absorption on the endogenous fluorescence signal intensity of biological tissues. Experimental studies were conducted to identify these effects. To register the fluorescence intensity, the fluorescence spectroscopy method was employed. The intensity of the blood flow was measured by laser Doppler flowmetry. We proposed one possible implementation of the Monte Carlo method for the theoretical analysis of the effect of blood on the fluorescence signals. The simulation is constructed as a four-layer skin optical model based on the known optical parameters of the skin with different levels of blood supply. With the help of the simulation, we demonstrate how the level of blood supply can affect the appearance of the fluorescence spectra. In addition, to describe the properties of biological tissue, which may affect the fluorescence spectra, we turned to the method of diffuse reflectance spectroscopy (DRS). Using the spectral data provided by the DRS, the tissue attenuation effect can be extracted and used to correct the fluorescence spectra.
Citations by journals
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1
2
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Regional blood circulation and microcirculation
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Regional blood circulation and microcirculation
2 publications, 28.57%
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Journal of Biomedical Optics
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Journal of Biomedical Optics
1 publication, 14.29%
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Optics and Spectroscopy (English translation of Optika i Spektroskopiya)
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Optics and Spectroscopy (English translation of Optika i Spektroskopiya)
1 publication, 14.29%
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Journal of Physics: Conference Series
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Journal of Physics: Conference Series
1 publication, 14.29%
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Laser Physics Letters
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Laser Physics Letters
1 publication, 14.29%
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Progress in Biomedical Optics and Imaging - Proceedings of SPIE
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Progress in Biomedical Optics and Imaging - Proceedings of SPIE
1 publication, 14.29%
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1
2
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Citations by publishers
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1
2
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SPIE
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SPIE
2 publications, 28.57%
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IOP Publishing
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IOP Publishing
2 publications, 28.57%
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First Pavlov State Medical University of St. Petersburg
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First Pavlov State Medical University of St. Petersburg
2 publications, 28.57%
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Pleiades Publishing
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Pleiades Publishing
1 publication, 14.29%
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1
2
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- We do not take into account publications that without a DOI.
- Statistics recalculated only for publications connected to researchers, organizations and labs registered on the platform.
- Statistics recalculated weekly.
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Zherebtsov E. A. et al. The development of attenuation compensation models of fluorescence spectroscopy signals // Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2016. Vol. 9917.
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Zherebtsov E. A., Rafailov I. E., Vinokurov A. Y., Novikova I. N., Zherebtsova A. I., Litvinova K. S., Dunaev A. V. The development of attenuation compensation models of fluorescence spectroscopy signals // Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2016. Vol. 9917.
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TY - CPAPER
DO - 10.1117/12.2229451
UR - https://doi.org/10.1117%2F12.2229451
TI - The development of attenuation compensation models of fluorescence spectroscopy signals
T2 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
AU - Zherebtsov, Evgeny A
AU - Rafailov, Ilya E.
AU - Vinokurov, Andrey Y.
AU - Novikova, Irina N
AU - Zherebtsova, Angelina I.
AU - Litvinova, Karina S.
AU - Dunaev, Andrey V.
PY - 2016
DA - 2016/04/21 00:00:00
PB - SPIE
VL - 9917
SN - 1605-7422
ER -
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@inproceedings{2016_Zherebtsov,
author = {Evgeny A Zherebtsov and Ilya E. Rafailov and Andrey Y. Vinokurov and Irina N Novikova and Angelina I. Zherebtsova and Karina S. Litvinova and Andrey V. Dunaev},
title = {The development of attenuation compensation models of fluorescence spectroscopy signals},
year = {2016},
volume = {9917},
month = {apr},
publisher = {SPIE}
}