Experimental modeling of local laser hyperthermia using thermosensitive nanoparticles absorbing in NIR

Igor Romanishkin 1
, 
Ilmo Sildos 1
, 
Daria V. Pominova 1
, 
Yuri V Orlovskii 1
, 
Victor B Loschenov 2
, 
Alexander S. Vanetsev 1
, 
Elena O Orlovskaya 1
, 
Pavel V Grachev 1
, 
Daria V Pominova 1
, 
Ivan A Burmistrov 1
1
 
2
 
Publication type: Proceedings Article
Publication date: 2018-04-26
—
Abstract
In this work we investigated the use of composite crystalline core/shell nanoparticles LaF3:Nd 3+ (1%)@DyPO4 for fluorescence-based contactless thermometry, as well as laser-induced hyperthermia effect in optical model of biological tissue with modeled neoplasm. In preparation for this, a thermal calibration of the nanoparticles luminescence spectra was carried out. The results of the spectroscopic temperature measurement were compared to infrared thermal camera measurements. It showed that there is a significant difference between temperature recorded with IR camera and the actual temperature of the nanoparticles in the depth of the tissue model. The temperature calculated using the spectral method was up to 10 °C higher.
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Romanishkin I. et al. Experimental modeling of local laser hyperthermia using thermosensitive nanoparticles absorbing in NIR // Saratov Fall Meeting 2017. 2018.
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Romanishkin I., Sildos I., Pominova D. V., Orlovskii Y. V., Loschenov V. B., Vanetsev A. S., Orlovskaya E. O., Grachev P. V., Pominova D. V., Burmistrov I. A. Experimental modeling of local laser hyperthermia using thermosensitive nanoparticles absorbing in NIR // Saratov Fall Meeting 2017. 2018.
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TY - CPAPER
DO - 10.1117/12.2309459
UR - https://doi.org/10.1117/12.2309459
TI - Experimental modeling of local laser hyperthermia using thermosensitive nanoparticles absorbing in NIR
T2 - Saratov Fall Meeting 2017
AU - Romanishkin, Igor
AU - Sildos, Ilmo
AU - Pominova, Daria V.
AU - Orlovskii, Yuri V
AU - Loschenov, Victor B
AU - Vanetsev, Alexander S.
AU - Orlovskaya, Elena O
AU - Grachev, Pavel V
AU - Pominova, Daria V
AU - Burmistrov, Ivan A
PY - 2018
DA - 2018/04/26
ER -
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@inproceedings{2018_Romanishkin,
author = {Igor Romanishkin and Ilmo Sildos and Daria V. Pominova and Yuri V Orlovskii and Victor B Loschenov and Alexander S. Vanetsev and Elena O Orlovskaya and Pavel V Grachev and Daria V Pominova and Ivan A Burmistrov},
title = {Experimental modeling of local laser hyperthermia using thermosensitive nanoparticles absorbing in NIR},
year = {2018},
month = {apr}
}