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Progress in Biomedical Optics and Imaging - Proceedings of SPIE, volume 11065
Fluorescence spectroscopy approach for blood influence compensation
2
Univ. of Oulu (Finland)
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Publication type: Proceedings Article
Publication date: 2019-06-03
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ISSN: 16057422
Abstract
At present, fluorescence spectroscopy (FS) and diffuse reflectance spectroscopy (DRS) are widespread methods highly used in medical practice. The combined application of these methods is a promising tool to improve the predictive force of classifiers for tissue type recognition as well as to compensate the attenuation of the fluorescence radiation by blood for the accurate evaluation of the biomarkers content in living tissue. Several techniques are known to normalize the resulting fluorescence spectrum in order to exclude the attenuation effect. In this study, an approach based on the dividing of the experimentally obtained FS spectrum by DRS spectrum has been applied for experiments with occlusion test. The implemented multimodal approach for the in vivo optical measurements in combination with occlusion test for minimisation of blood influence has shown good repeatability of obtained experimental fluorescence spectra. The results are of particular interest for the further development of methods for compensating the influence of chromophores in optical spectroscopy.
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Shupletsov V. et al. Fluorescence spectroscopy approach for blood influence compensation // Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2019. Vol. 11065.
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Shupletsov V., Zherebtsov E., Mezentsev M., Kozlov I., Potapova E., Dunaev A. Fluorescence spectroscopy approach for blood influence compensation // Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2019. Vol. 11065.
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TY - CPAPER
DO - 10.1117/12.2522794
UR - https://doi.org/10.1117%2F12.2522794
TI - Fluorescence spectroscopy approach for blood influence compensation
T2 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
AU - Shupletsov, Valerii
AU - Zherebtsov, Evgeny
AU - Mezentsev, Mikhail
AU - Kozlov, Igor
AU - Potapova, Elena
AU - Dunaev, Andrey
PY - 2019
DA - 2019/06/03 00:00:00
PB - SPIE
VL - 11065
SN - 1605-7422
ER -
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@inproceedings{2019_Shupletsov,
author = {Valerii Shupletsov and Evgeny Zherebtsov and Mikhail Mezentsev and Igor Kozlov and Elena Potapova and Andrey Dunaev},
title = {Fluorescence spectroscopy approach for blood influence compensation},
year = {2019},
volume = {11065},
month = {jun},
publisher = {SPIE}
}