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Proceedings of SPIE - The International Society for Optical Engineering, volume 11363

Optical fine needle biopsy in hepatocellular carcinoma mouse model

Alekseyev Alexander G 1
Mamoshin Andrian V 1, 3
Ivanov Yuri 4, 5
Panchenkov Dmitry 6
2
 
Univ. of Oulu (Finland)
3
 
Orel Regional Clinical Hospital (Russian Federation)
4
 
Central Research Institute of Tuberculosis (Russian Federation)
5
 
Federal Scientific and Clinical Ctr. for Specialized Medical Service and Medical Technologies (Russian Federation)
Publication typeProceedings Article
Publication date2020-04-02
Quartile SCImago
Quartile WOS
Impact factor
ISSN0277786X, 1996756X
Abstract
The paper describes the results of experimental studies using custom developed optical biopsy system for diagnostics in vivo during the procedure of fine needle aspiration biopsy. Experimental studies were conducted in laboratory mice with inoculated hepatocellular carcinoma. The measurements were carried out using fluorescence spectroscopy and diffuse reflectance spectroscopy methods to reveal metabolic and morphological changes in tissues. The results show that the developed approach is sensitive for cancer detection. Quantified differences in the maximum of fluorescence spectra and diffuse reflectance spectra between tumor and normal tissues were demonstrated and approved with morphological analysis.
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Potapova E. V. et al. Optical fine needle biopsy in hepatocellular carcinoma mouse model // Proceedings of SPIE - The International Society for Optical Engineering. 2020. Vol. 11363.
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Potapova E. V., Kandurova K. Y., Shupletsov V. V., Seryogina E., Zherebtsov E. A., Alekseyev A. G., Mamoshin A. V., Ivanov Y., Panchenkov D., Dunaev A. V. Optical fine needle biopsy in hepatocellular carcinoma mouse model // Proceedings of SPIE - The International Society for Optical Engineering. 2020. Vol. 11363.
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TY - CPAPER
DO - 10.1117/12.2555154
UR - https://doi.org/10.1117%2F12.2555154
TI - Optical fine needle biopsy in hepatocellular carcinoma mouse model
T2 - Proceedings of SPIE - The International Society for Optical Engineering
AU - Potapova, Elena V
AU - Kandurova, Ksenia Y
AU - Shupletsov, Valery V
AU - Seryogina, Evgeniya
AU - Zherebtsov, Evgenii A
AU - Alekseyev, Alexander G
AU - Mamoshin, Andrian V
AU - Ivanov, Yuri
AU - Panchenkov, Dmitry
AU - Dunaev, Andrey V.
PY - 2020
DA - 2020/04/02 00:00:00
PB - SPIE
VL - 11363
SN - 0277-786X
SN - 1996-756X
ER -
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@inproceedings{2020_Potapova,
author = {Elena V Potapova and Ksenia Y Kandurova and Valery V Shupletsov and Evgeniya Seryogina and Evgenii A Zherebtsov and Alexander G Alekseyev and Andrian V Mamoshin and Yuri Ivanov and Dmitry Panchenkov and Andrey V. Dunaev},
title = {Optical fine needle biopsy in hepatocellular carcinoma mouse model},
year = {2020},
volume = {11363},
month = {apr},
publisher = {SPIE}
}
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