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Proceedings of SPIE - The International Society for Optical Engineering, volume 11363
Liposomal nanoparticles enhance contrast of fluorescence, specklecontrast imaging, and ultrasound measurements in phantoms and murine model
Stelmashchuk Olga A
1
,
Vinokurov Andrey
1
,
Аpanaykin Mikhail
2
,
Kozlov Igor
2
,
Mamoshin Andrian
1
,
Borsukov Alexey
3
,
Publication type: Proceedings Article
Publication date: 2020-04-02
Quartile SCImago
— Quartile WOS
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Impact factor: —
ISSN: 0277786X, 1996756X
Abstract
Liposomal particles are used as an instrument for drug delivery and as fluorescent labels. Due to its properties, liposomal particles can be used as a dual-purpose contrast agent both in fluorescence imaging, laser speckle contrast imaging and ultrasound diagnostics. Liposomes obtained by one purpose but subsequently contained a fluorescent label or air. This work aimed to prepare liposomal particles and to study possibilities of its application for the dual-use in fluorescence spectroscopy and ultrasound diagnostics. In this work, we used fluorescence spectroscopy to investigate the efficiency of propagation in the circulatory system of fluorescent-labelled liposome nanocapsules loaded with eosin-Y (disodium salt of 2,4,5,7 tetrabromofluorescein These results demonstrate that liposomal particles can be used in fluorescence spectroscopy, in ultrasound diagnostics and in LSCI. It may find the application in the field of drug delivery control and high-throughput screening during drug development.
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Stelmashchuk O. A. et al. Liposomal nanoparticles enhance contrast of fluorescence, specklecontrast imaging, and ultrasound measurements in phantoms and murine model // Proceedings of SPIE - The International Society for Optical Engineering. 2020. Vol. 11363.
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Stelmashchuk O. A., Vinokurov A., Аpanaykin M., Kozlov I., Mamoshin A., Borsukov A., Dunaev A. V. Liposomal nanoparticles enhance contrast of fluorescence, specklecontrast imaging, and ultrasound measurements in phantoms and murine model // Proceedings of SPIE - The International Society for Optical Engineering. 2020. Vol. 11363.
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TY - CPAPER
DO - 10.1117/12.2555973
UR - https://doi.org/10.1117%2F12.2555973
TI - Liposomal nanoparticles enhance contrast of fluorescence, specklecontrast imaging, and ultrasound measurements in phantoms and murine model
T2 - Proceedings of SPIE - The International Society for Optical Engineering
AU - Stelmashchuk, Olga A
AU - Vinokurov, Andrey
AU - Аpanaykin, Mikhail
AU - Kozlov, Igor
AU - Mamoshin, Andrian
AU - Borsukov, Alexey
AU - Dunaev, Andrey V.
PY - 2020
DA - 2020/04/02 00:00:00
PB - SPIE
VL - 11363
SN - 0277-786X
SN - 1996-756X
ER -
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@inproceedings{2020_Stelmashchuk
author = {Olga A Stelmashchuk and Andrey Vinokurov and Mikhail Аpanaykin and Igor Kozlov and Andrian Mamoshin and Alexey Borsukov and Andrey V. Dunaev},
title = {Liposomal nanoparticles enhance contrast of fluorescence, specklecontrast imaging, and ultrasound measurements in phantoms and murine model},
year = {2020},
volume = {11363},
month = {apr},
publisher = {SPIE}
}