Methodology of Microcirculatory-Tissue Systems Multimodal Optical Diagnostics

A modern trend in the development of optical non-invasive diagnostics (OND), which makes it possible to reduce the number of disadvantages in individual applications of methods, is a multimodal approach when one diagnostic technology combines various optical and other physical research methods, which makes it possible to provide early diagnosis of functional changes before clinical manifestations of the disease based on the measurement results. In the last decade, there has been a steady increase in interest in the problems of non-invasive research of microcirculatory tissue systems (MTS) of the human body, which is due to their significant role in the pathogenesis of various diseases. For a wider introduction of OND technologies into clinical practice, it is necessary to further improve the methodology of the multimodal approach in the development of new methods and technical means for assessing the functional state of MTS in various fields of medicine.