Open Access

Science advances, volume 6, issue 11

An array of 60,000 antibodies for proteome-scale antibody generation and target discovery

Zhaohui Wang ^{1, 2}

Yang Li ³

Bing Hou ^{1, 2}

Mira I Pronobis ⁴

Mingqiao Wang ²

Yuemeng Wang ²

Guangcun Cheng ²

Weining Weng ²

Yiqiang Wang ²

Yanfang Tang ²

Xuefan XU ²

Rong Pan ²

Fei Lin ²

Nan Wang ³

Ziqing Chen ³

Shiwei Wang ⁵

Luyan Zulie Ma ⁵

Yang Rui Li ⁶

Dongliang Huang ⁶

Li Jiang ⁷

Zhiqiang Wang ⁸

Wenfang Zeng ⁸

Ying Zhang ⁸

Xuemei Du ⁹

Ying Lin ¹⁰

Zhiqing Li ¹⁰

Qingyou Xia ¹⁰

Jing Geng ¹¹

Huaping Dai ¹¹

Yu Yuan ¹

Xiaodong Zhao ¹²

Zheng Yuan ¹³

Jian Yan ^{14, 15}

Qinghua Nie ^{16, 17}

Xiquan Zhang ^{16, 17}

Kun Wang ¹⁸

Fulin Chen ¹

Qin Zhang ⁷

Yuxian Zhu ¹⁸

Susan Zheng ⁴

Kenneth Poss ⁴

Sheng Tao ^{3, 12, 19}

Xun Meng ^{1, 2}

Show full list: 43 authors

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School of Life Sciences, Northwest University, Xi’an, Shanxi 710069, China. |

Abmart, 333 Guiping Road, Shanghai 200033, China. |

Shanghai Center for Systems Biomedicine, Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200240, China. |

⁴

Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA. |

⁵

State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China. |

⁶

Guangxi Key Laboratory of Sugarcane Genetic Improvement/Key Laboratory of Sugarcane Biotechnology and Genetic Improvement (Guangxi), Ministry of Agriculture, Nanning, Guangxi 530007, China. |

⁷

Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture and National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China. |

⁸

Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, Henan 450009, China. |

⁹

Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing 100083, China. |

¹⁰

State Key Laboratory of Silkworm Genome Biology, Southwest University, Chongqing 400716, China. |

¹¹

Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, National Clinical Research Center for Respiratory Diseases, Beijing 100029, China. |

¹²

School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China. |

¹³

School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China. |

¹⁴

Ludwig Institute for Cancer Research, 9500 Gilman Dr., La Jolla, CA 92093, USA. |

¹⁵

Department of Medical Biochemistry and Biophysics, Division of Functional Genomics and Systems Biology, Karolinska Institutet, 171 65 Stockholm, Sweden. |

¹⁶

College of Animal Science, South China Agricultural University, Guangzhou, Guangdong 510642, China. |

¹⁷

Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, and Key Laboratory of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture, South China Agricultural University, Guangzhou, Guangdong 510642, China. |

¹⁸

Institute for Advanced Studies and College of Life Sciences, Wuhan University, Wuhan, China. |

¹⁹

State Key Laboratory of Oncogenes and Related Genes, Shanghai 200240, China. |

Publication type: Journal Article

Publication date: 2020-03-13

American Association for the Advancement of Science (AAAS)

Journal: Science advances

scimago Q1

SJR: 4.483

CiteScore: 21.4

Impact factor: 11.7

ISSN: 23752548

DOI: 10.1126/sciadv.aax2271

Copy DOI

PubMed ID: 32195335

Multidisciplinary

Abstract

A massively parallel array of monoclonal antibodies enables rapid antibody development and target discovery across species.

Found

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eLife	eLife, 2, 7.69% eLife 2 publications, 7.69%
International Journal of Oncology	International Journal of Oncology, 1, 3.85% International Journal of Oncology 1 publication, 3.85%
Technology in Cancer Research and Treatment	Technology in Cancer Research and Treatment, 1, 3.85% Technology in Cancer Research and Treatment 1 publication, 3.85%
Frontiers in Cell and Developmental Biology	Frontiers in Cell and Developmental Biology, 1, 3.85% Frontiers in Cell and Developmental Biology 1 publication, 3.85%
Genomics, Proteomics and Bioinformatics	Genomics, Proteomics and Bioinformatics, 1, 3.85% Genomics, Proteomics and Bioinformatics 1 publication, 3.85%
Cell Reports	Cell Reports, 1, 3.85% Cell Reports 1 publication, 3.85%
Angewandte Chemie - International Edition	Angewandte Chemie - International Edition, 1, 3.85% Angewandte Chemie - International Edition 1 publication, 3.85%
Angewandte Chemie	Angewandte Chemie, 1, 3.85% Angewandte Chemie 1 publication, 3.85%
Proteomics	Proteomics, 1, 3.85% Proteomics 1 publication, 3.85%
Cancer Medicine	Cancer Medicine, 1, 3.85% Cancer Medicine 1 publication, 3.85%
Proteomics - Clinical Applications	Proteomics - Clinical Applications, 1, 3.85% Proteomics - Clinical Applications 1 publication, 3.85%
Journal of Proteome Research	Journal of Proteome Research, 1, 3.85% Journal of Proteome Research 1 publication, 3.85%
Plants	Plants, 1, 3.85% Plants 1 publication, 3.85%
Acta Horticulturae	Acta Horticulturae, 1, 3.85% Acta Horticulturae 1 publication, 3.85%
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International Journal of Biological Macromolecules	International Journal of Biological Macromolecules, 1, 3.85% International Journal of Biological Macromolecules 1 publication, 3.85%
Cancer Research	Cancer Research, 1, 3.85% Cancer Research 1 publication, 3.85%
Plant Physiology	Plant Physiology, 1, 3.85% Plant Physiology 1 publication, 3.85%
Journal of Hazardous Materials	Journal of Hazardous Materials, 1, 3.85% Journal of Hazardous Materials 1 publication, 3.85%
Frontiers in Bioinformatics	Frontiers in Bioinformatics, 1, 3.85% Frontiers in Bioinformatics 1 publication, 3.85%
Advanced Functional Materials	Advanced Functional Materials, 1, 3.85% Advanced Functional Materials 1 publication, 3.85%
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Wiley	Wiley, 6, 23.08% Wiley 6 publications, 23.08%
Elsevier	Elsevier, 4, 15.38% Elsevier 4 publications, 15.38%
Frontiers Media S.A.	Frontiers Media S.A., 2, 7.69% Frontiers Media S.A. 2 publications, 7.69%
Cold Spring Harbor Laboratory	Cold Spring Harbor Laboratory, 2, 7.69% Cold Spring Harbor Laboratory 2 publications, 7.69%
eLife Sciences Publications	eLife Sciences Publications, 2, 7.69% eLife Sciences Publications 2 publications, 7.69%
Spandidos Publications	Spandidos Publications, 1, 3.85% Spandidos Publications 1 publication, 3.85%
SAGE	SAGE, 1, 3.85% SAGE 1 publication, 3.85%
American Chemical Society (ACS)	American Chemical Society (ACS), 1, 3.85% American Chemical Society (ACS) 1 publication, 3.85%
MDPI	MDPI, 1, 3.85% MDPI 1 publication, 3.85%
International Society for Horticultural Science (ISHS)	International Society for Horticultural Science (ISHS), 1, 3.85% International Society for Horticultural Science (ISHS) 1 publication, 3.85%
European Molecular Biology Organization	European Molecular Biology Organization, 1, 3.85% European Molecular Biology Organization 1 publication, 3.85%
IntechOpen	IntechOpen, 1, 3.85% IntechOpen 1 publication, 3.85%
American Association for Cancer Research (AACR)	American Association for Cancer Research (AACR), 1, 3.85% American Association for Cancer Research (AACR) 1 publication, 3.85%
Oxford University Press	Oxford University Press, 1, 3.85% Oxford University Press 1 publication, 3.85%
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Publisher

American Association for the Advancement of Science (AAAS)

Journal

Science advances

scimago Q1

SJR

4.483

CiteScore

21.4

Impact factor

11.7

ISSN

23752548 (Electronic)

An array of 60,000 antibodies for proteome-scale antibody generation and target discovery

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