Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair
K J. Mylonas
1
,
Eoin D. O’Sullivan
1
,
Duncan C. Humphries
1
,
David P. Baird
1, 2
,
Marie Helena Docherty
1
,
Sarah A Neely
1, 3
,
Paul J Krimpenfort
4
,
A. Melk
5
,
Roland Schmitt
5
,
Sofia Ferreira Gonzalez
3
,
SUSAN FORBES
3
,
Jeremy A. Hughes
1
,
D Ferenbach
1
2
Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.
|
Publication type: Journal Article
Publication date: 2021-05-19
scimago Q1
wos Q1
SJR: 6.722
CiteScore: 27.9
Impact factor: 14.6
ISSN: 19466234, 19466242
PubMed ID:
34011625
General Medicine
Abstract
Senescent renal epithelia promote fibrosis and functional loss after injury, whereas depletion improves regeneration in aged or irradiated kidneys.
Found
Nothing found, try to update filter.
Found
Nothing found, try to update filter.
Top-30
Journals
|
1
2
3
4
5
6
|
|
|
Nature Reviews Nephrology
6 publications, 3.92%
|
|
|
Cells
5 publications, 3.27%
|
|
|
Nature Communications
5 publications, 3.27%
|
|
|
International Journal of Molecular Sciences
4 publications, 2.61%
|
|
|
JCI insight
3 publications, 1.96%
|
|
|
Journal of the American Society of Nephrology : JASN
3 publications, 1.96%
|
|
|
Cell Death Discovery
3 publications, 1.96%
|
|
|
Aging Cell
3 publications, 1.96%
|
|
|
American Journal of Physiology - Renal Physiology
3 publications, 1.96%
|
|
|
GeroScience
3 publications, 1.96%
|
|
|
Current Opinion in Nephrology and Hypertension
2 publications, 1.31%
|
|
|
Frontiers in Immunology
2 publications, 1.31%
|
|
|
Frontiers in Endocrinology
2 publications, 1.31%
|
|
|
Mechanisms of Ageing and Development
2 publications, 1.31%
|
|
|
American Journal of Transplantation
2 publications, 1.31%
|
|
|
Nature Aging
2 publications, 1.31%
|
|
|
Autophagy
2 publications, 1.31%
|
|
|
Biochemical and Biophysical Research Communications
2 publications, 1.31%
|
|
|
Frontiers in Cardiovascular Medicine
2 publications, 1.31%
|
|
|
Kidney360
2 publications, 1.31%
|
|
|
Frontiers in Cell and Developmental Biology
2 publications, 1.31%
|
|
|
MedComm
2 publications, 1.31%
|
|
|
FASEB Journal
2 publications, 1.31%
|
|
|
Science Translational Medicine
2 publications, 1.31%
|
|
|
Frontiers in Pharmacology
2 publications, 1.31%
|
|
|
CKJ: Clinical Kidney Journal
2 publications, 1.31%
|
|
|
Chinese Medical Journal
2 publications, 1.31%
|
|
|
The Lancet Healthy Longevity
1 publication, 0.65%
|
|
|
Die Diabetologie
1 publication, 0.65%
|
|
|
1
2
3
4
5
6
|
Publishers
|
5
10
15
20
25
30
35
40
|
|
|
Springer Nature
37 publications, 24.18%
|
|
|
Elsevier
21 publications, 13.73%
|
|
|
Wiley
17 publications, 11.11%
|
|
|
Frontiers Media S.A.
12 publications, 7.84%
|
|
|
MDPI
11 publications, 7.19%
|
|
|
Ovid Technologies (Wolters Kluwer Health)
9 publications, 5.88%
|
|
|
Taylor & Francis
8 publications, 5.23%
|
|
|
Cold Spring Harbor Laboratory
8 publications, 5.23%
|
|
|
Oxford University Press
5 publications, 3.27%
|
|
|
American Physiological Society
4 publications, 2.61%
|
|
|
American Society for Clinical Investigation
3 publications, 1.96%
|
|
|
American Association for the Advancement of Science (AAAS)
3 publications, 1.96%
|
|
|
Royal Society of Chemistry (RSC)
2 publications, 1.31%
|
|
|
American Society of Nephrology
1 publication, 0.65%
|
|
|
eLife Sciences Publications
1 publication, 0.65%
|
|
|
Mark Allen Group
1 publication, 0.65%
|
|
|
Portland Press
1 publication, 0.65%
|
|
|
Research Square Platform LLC
1 publication, 0.65%
|
|
|
Proceedings of the National Academy of Sciences (PNAS)
1 publication, 0.65%
|
|
|
Mary Ann Liebert
1 publication, 0.65%
|
|
|
American Association for Cancer Research (AACR)
1 publication, 0.65%
|
|
|
American Chemical Society (ACS)
1 publication, 0.65%
|
|
|
5
10
15
20
25
30
35
40
|
- We do not take into account publications without a DOI.
- Statistics recalculated weekly.
Are you a researcher?
Create a profile to get free access to personal recommendations for colleagues and new articles.
Metrics
153
Total citations:
153
Citations from 2024:
86
(56.21%)
Cite this
GOST |
RIS |
BibTex
Cite this
GOST
Copy
Mylonas K. J. et al. Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair // Science Translational Medicine. 2021. Vol. 13. No. 594.
GOST all authors (up to 50)
Copy
Mylonas K. J., O’Sullivan E. D., Humphries D. C., Baird D. P., Docherty M. H., Neely S. A., Krimpenfort P. J., Melk A., Schmitt R., Ferreira Gonzalez S., FORBES S., Hughes J. A., Ferenbach D. Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair // Science Translational Medicine. 2021. Vol. 13. No. 594.
Cite this
RIS
Copy
TY - JOUR
DO - 10.1126/scitranslmed.abb0203
UR - https://doi.org/10.1126/scitranslmed.abb0203
TI - Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair
T2 - Science Translational Medicine
AU - Mylonas, K J.
AU - O’Sullivan, Eoin D.
AU - Humphries, Duncan C.
AU - Baird, David P.
AU - Docherty, Marie Helena
AU - Neely, Sarah A
AU - Krimpenfort, Paul J
AU - Melk, A.
AU - Schmitt, Roland
AU - Ferreira Gonzalez, Sofia
AU - FORBES, SUSAN
AU - Hughes, Jeremy A.
AU - Ferenbach, D
PY - 2021
DA - 2021/05/19
PB - American Association for the Advancement of Science (AAAS)
IS - 594
VL - 13
PMID - 34011625
SN - 1946-6234
SN - 1946-6242
ER -
Cite this
BibTex (up to 50 authors)
Copy
@article{2021_Mylonas,
author = {K J. Mylonas and Eoin D. O’Sullivan and Duncan C. Humphries and David P. Baird and Marie Helena Docherty and Sarah A Neely and Paul J Krimpenfort and A. Melk and Roland Schmitt and Sofia Ferreira Gonzalez and SUSAN FORBES and Jeremy A. Hughes and D Ferenbach},
title = {Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair},
journal = {Science Translational Medicine},
year = {2021},
volume = {13},
publisher = {American Association for the Advancement of Science (AAAS)},
month = {may},
url = {https://doi.org/10.1126/scitranslmed.abb0203},
number = {594},
doi = {10.1126/scitranslmed.abb0203}
}