volume 8 issue 325

Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo

Susan Ashton 1
Young-Ho Song 2
Jim Nolan 2
Elaine Cadogan 1
Jim Murray 3
RAJESH ODEDRA 1
John Foster 4
Peter A. Hall 4
Susan Low 2
Paula Taylor 1
Rebecca Ellston 1
Urszula M. Polanska 1
Joanne Wilson 1
Colin Howes 1
Aaron Smith 1
Richard J. A. Goodwin 4
John G Swales 4
Nicole Strittmatter 5
Zoltán Takáts 5
Anna Nilsson 6
Per Andrén 6
Dawn Trueman 1
Mike Walker 1
Corinne L Reimer 7
Greg Troiano 2
Donald Parsons 2
David De Witt 2
Marianne Ashford 3
Jeff Hrkach 2
Stephen Zale 2
Philip J. Jewsbury 1
Simon T. BARRY 1
Publication typeJournal Article
Publication date2016-02-10
scimago Q1
wos Q1
SJR6.722
CiteScore27.9
Impact factor14.6
ISSN19466234, 19466242
General Medicine
Abstract

A nanoparticle formulation of an Aurora B kinase inhibitor uses ion pairing to achieve controlled release and efficacious, nontoxic target inhibition in tumors.

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GOST |
Cite this
GOST Copy
Ashton S. et al. Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo // Science Translational Medicine. 2016. Vol. 8. No. 325.
GOST all authors (up to 50) Copy
Ashton S., Song Y., Nolan J., Cadogan E., Murray J., ODEDRA R., Foster J., Hall P. A., Low S., Taylor P., Ellston R., Polanska U. M., Wilson J., Howes C., Smith A., Goodwin R. J. A., Swales J. G., Strittmatter N., Takáts Z., Nilsson A., Andrén P., Trueman D., Walker M., Reimer C. L., Troiano G., Parsons D., De Witt D., Ashford M., Hrkach J., Zale S., Jewsbury P. J., BARRY S. T. Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo // Science Translational Medicine. 2016. Vol. 8. No. 325.
RIS |
Cite this
RIS Copy
TY - JOUR
DO - 10.1126/scitranslmed.aad2355
UR - https://doi.org/10.1126/scitranslmed.aad2355
TI - Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo
T2 - Science Translational Medicine
AU - Ashton, Susan
AU - Song, Young-Ho
AU - Nolan, Jim
AU - Cadogan, Elaine
AU - Murray, Jim
AU - ODEDRA, RAJESH
AU - Foster, John
AU - Hall, Peter A.
AU - Low, Susan
AU - Taylor, Paula
AU - Ellston, Rebecca
AU - Polanska, Urszula M.
AU - Wilson, Joanne
AU - Howes, Colin
AU - Smith, Aaron
AU - Goodwin, Richard J. A.
AU - Swales, John G
AU - Strittmatter, Nicole
AU - Takáts, Zoltán
AU - Nilsson, Anna
AU - Andrén, Per
AU - Trueman, Dawn
AU - Walker, Mike
AU - Reimer, Corinne L
AU - Troiano, Greg
AU - Parsons, Donald
AU - De Witt, David
AU - Ashford, Marianne
AU - Hrkach, Jeff
AU - Zale, Stephen
AU - Jewsbury, Philip J.
AU - BARRY, Simon T.
PY - 2016
DA - 2016/02/10
PB - American Association for the Advancement of Science (AAAS)
IS - 325
VL - 8
PMID - 26865565
SN - 1946-6234
SN - 1946-6242
ER -
BibTex
Cite this
BibTex (up to 50 authors) Copy
@article{2016_Ashton,
author = {Susan Ashton and Young-Ho Song and Jim Nolan and Elaine Cadogan and Jim Murray and RAJESH ODEDRA and John Foster and Peter A. Hall and Susan Low and Paula Taylor and Rebecca Ellston and Urszula M. Polanska and Joanne Wilson and Colin Howes and Aaron Smith and Richard J. A. Goodwin and John G Swales and Nicole Strittmatter and Zoltán Takáts and Anna Nilsson and Per Andrén and Dawn Trueman and Mike Walker and Corinne L Reimer and Greg Troiano and Donald Parsons and David De Witt and Marianne Ashford and Jeff Hrkach and Stephen Zale and Philip J. Jewsbury and Simon T. BARRY},
title = {Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo},
journal = {Science Translational Medicine},
year = {2016},
volume = {8},
publisher = {American Association for the Advancement of Science (AAAS)},
month = {feb},
url = {https://doi.org/10.1126/scitranslmed.aad2355},
number = {325},
doi = {10.1126/scitranslmed.aad2355}
}