, volume 88 , issue 9 , pages 5171-5176

Functional Rectification of the Newly Described African Henipavirus Fusion Glycoprotein (Gh-M74a)

Olivier Pernet ¹

Shannon Beaty ¹

Benhur Lee ^{1, 2}

Hide authors affiliations Show authors affiliations: 2 affiliations

Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA |

Icahn School of Medicine at Mount Sinai, New York, New York, USA |

Publication type: Journal Article

Publication date: 2014-05-09

American Society for Microbiology

Journal of Virology

scimago Q1

wos Q2

SJR: 1.283

CiteScore: 7.8

Impact factor: 3.8

ISSN: 0022538X, 10985514

DOI: 10.1128/jvi.03655-13

Copy DOI

PubMed ID: 24522929

Microbiology

Immunology

Insect Science

Virology

Abstract

ABSTRACT

Recent evidence identified multiple Henipavirus species in Africa distinct from those in Southeast Asia and Australia. The reported fusion glycoprotein (F) sequence of the African Gh-M74a strain (GhV-F) is likely incorrect: a single base pair deletion near the N terminus results in multiple aberrancies. Rectifying this by adding single nucleotide insertions results in a GhV-F that now possesses a signal peptide, is efficiently cell surface expressed, exhibits syncytium formation when coexpressed with GhV-G protein, and mediates pseudotyped viral particle entry.

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GOST |

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GOST Copy

Pernet O. et al. Functional Rectification of the Newly Described African Henipavirus Fusion Glycoprotein (Gh-M74a) // Journal of Virology. 2014. Vol. 88. No. 9. pp. 5171-5176.

GOST all authors (up to 50) Copy

Pernet O., Beaty S., Lee B. Functional Rectification of the Newly Described African Henipavirus Fusion Glycoprotein (Gh-M74a) // Journal of Virology. 2014. Vol. 88. No. 9. pp. 5171-5176.

RIS |

Cite this

RIS Copy

TY - JOUR

DO - 10.1128/jvi.03655-13

UR - https://doi.org/10.1128/jvi.03655-13

TI - Functional Rectification of the Newly Described African Henipavirus Fusion Glycoprotein (Gh-M74a)

T2 - Journal of Virology

AU - Pernet, Olivier

AU - Beaty, Shannon

AU - Lee, Benhur

PY - 2014

DA - 2014/05/09

PB - American Society for Microbiology

SP - 5171-5176

IS - 9

VL - 88

PMID - 24522929

SN - 0022-538X

SN - 1098-5514

ER -

BibTex |

Cite this

BibTex (up to 50 authors) Copy

@article{2014_Pernet,

author = {Olivier Pernet and Shannon Beaty and Benhur Lee},

title = {Functional Rectification of the Newly Described African Henipavirus Fusion Glycoprotein (Gh-M74a)},

journal = {Journal of Virology},

year = {2014},

volume = {88},

publisher = {American Society for Microbiology},

month = {may},

url = {https://doi.org/10.1128/jvi.03655-13},

number = {9},

pages = {5171--5176},

doi = {10.1128/jvi.03655-13}

}

MLA

Cite this

MLA Copy

Pernet, Olivier, et al. “Functional Rectification of the Newly Described African Henipavirus Fusion Glycoprotein (Gh-M74a).” Journal of Virology, vol. 88, no. 9, May. 2014, pp. 5171-5176. https://doi.org/10.1128/jvi.03655-13.

Publisher

American Society for Microbiology

Journal

Journal of Virology

scimago Q1

wos Q2

SJR

1.283

CiteScore

7.8

Impact factor

3.8

ISSN

0022538X (Print)

10985514 (Electronic)