Open Access
Open access
mBio, volume 12, issue 4

Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages

Publication typeJournal Article
Publication date2021-08-31
Journal: mBio
scimago Q1
SJR2.028
CiteScore10.5
Impact factor5.1
ISSN21612129, 21507511
Microbiology
Virology
Abstract

Mycobacterium tuberculosis (Mtb) infects one-quarter of the global population and causes one of the deadliest infectious diseases worldwide. Macrophages are the first line of defense against Mtb infection and are typically incredibly efficient at destroying intracellular pathogens, but Mtb has evolved to survive and replicate in this harsh environment.

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